3(2H)-Pyridazinone, 4-acetyl-5,6-bis(4-chlorophenyl)-2-methyl-

Base Information

Chemical Name:3(2H)-Pyridazinone, 4-acetyl-5,6-bis(4-chlorophenyl)-2-methyl-
CAS No.:78612-99-4
Molecular Formula:C₁₉H₁₄Cl₂N₂O₂
Molecular Weight:373.238
Hs Code.:
DSSTox Substance ID:DTXSID50229204
Wikidata:Q83109414

Synonyms:4-Acetyl-5,6-bis(4-chlorophenyl)-2-methyl-3(2H)-pyridazinone;3(2H)-Pyridazinone, 4-acetyl-5,6-bis(4-chlorophenyl)-2-methyl-;78612-99-4;C19H14Cl2N2O2;DTXSID50229204;C19-H14-Cl2-N2-O2;LS-129736

Suppliers and Price of 3(2H)-Pyridazinone, 4-acetyl-5,6-bis(4-chlorophenyl)-2-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3(2H)-Pyridazinone, 4-acetyl-5,6-bis(4-chlorophenyl)-2-methyl-

Chemical Property:

Vapor Pressure:6.11E-11mmHg at 25°C
Refractive Index:1.633
Boiling Point:520.7°C at 760 mmHg
Flash Point:268.7°C
Density:1.33g/cm³
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:372.0432331
Heavy Atom Count:25
Complexity:613

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C(=NN(C1=O)C)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl

Technology Process of 3(2H)-Pyridazinone, 4-acetyl-5,6-bis(4-chlorophenyl)-2-methyl-

There total 2 articles about 3(2H)-Pyridazinone, 4-acetyl-5,6-bis(4-chlorophenyl)-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 75643-31-1
4-Acetyl-5,6-bis(p-chlorophenyl)-2H-pyridazin-3-one

: 74-88-4
methyl iodide

: 78612-99-4
4-acetyl-5,6-bis(4-chlorophenyl)-2-methyl-2H-pyridazin-3-one

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 18h;
DOI:10.1002/jps.2600700419

Reference yield:

: 40036-75-7
(E)-4,4'-dichlorobenzil monohydrazone

: 78612-99-4
4-acetyl-5,6-bis(4-chlorophenyl)-2-methyl-2H-pyridazin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / xylene / 7 h / 110 - 136 °C

2: 63 percent / potassium carbonate / dimethylformamide / 18 h / 80 °C

With pyridine; potassium carbonate; In N,N-dimethyl-formamide; xylene;
DOI:10.1002/jps.2600700419