10-Phenylphenoxaphosphine 10-oxide

Base Information

• Chemical Name: 10-Phenylphenoxaphosphine 10-oxide
• CAS No.: 1091-27-6
• Molecular Formula: C18H13 O2 P
• Molecular Weight: 292.274
• NSC Number: 87210
• DSSTox Substance ID: DTXSID30293100
• Nikkaji Number: J425.438D
• Wikidata: Q82031699
• Mol file: 1091-27-6.mol

Synonyms:10-Phenylphenoxaphosphine 10-oxide;1091-27-6;Phenoxaphosphine, 10-oxide;SCHEMBL19276652;10H-Phenoxaphosphine, 10-oxide;DTXSID30293100;NSC87210;NSC-87210

Chemical Property of 10-Phenylphenoxaphosphine 10-oxide

Chemical Property:

• Vapor Pressure: 2.75E-09mmHg at 25°C
• Boiling Point: 490.4°C at 760 mmHg
• Flash Point: 263.6°C
• Density: 1.31g/cm³
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 292.06531665
• Heavy Atom Count: 21
• Complexity: 389

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P2(=O)C3=CC=CC=C3OC4=CC=CC=C24

Technology Process of 10-Phenylphenoxaphosphine 10-oxide

There total 12 articles about 10-Phenylphenoxaphosphine 10-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

10-phenyl-10H-phenoxaphosphinine (1225-16-7) → 10-phenyl-10λ5-phenoxaphosphine 10-oxide (1091-27-6)

Guidance literature:

With dihydrogen peroxide; In ethanol; for 0.166667h;

Reference yield: 94.0%

bis[2-(diphenylphosphino)phenyl] ether (166330-10-5) → 10-phenyl-10λ5-phenoxaphosphine 10-oxide (1091-27-6)

Guidance literature:

bis[2-(diphenylphosphino)phenyl] ether; With bis(η3-allyl-μ-chloropalladium(II)); In toluene; at 140 ℃; for 24h; Sealed tube; Inert atmosphere;

With dihydrogen peroxide; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1246/cl.170581

Reference yield:

1-(2-bromophenoxy)-2-nitrobenzene (60671-89-8) → 10-phenyl-10λ5-phenoxaphosphine 10-oxide (1091-27-6)

Guidance literature:

Multi-step reaction with 4 steps

1: iron; aq.-ethanolic HCl

2: sodium nitrite; aqueous hydrobromic acid / Eintragen der Reaktionsloesung in ein heisses Gemisch von Kupfer(I)-bromid und wss. Bromwasserstoffsaeure

3: butyllithium; benzene; petroleum ether

4: aqueous H₂O₂; acetone

With hydrogenchloride; n-butyllithium; hydrogen bromide; dihydrogen peroxide; iron; acetone; Petroleum ether; sodium nitrite; benzene;

DOI:10.1039/jr9530003746

upstream raw materials:

10-phenyl-10H-phenoxaphosphinine

bis(2-methoxyphenyl)(phenyl) phosphine oxide

diphenylether

o,o'-dilithio-diphenyl ether

Downstream raw materials:

phenyl(o-phenoxyphenyl)phosphinic acid

2-hydroxyphenyl(phenyl)phosphinic acid

bis(2-hydroxyphenyl)phenyl-λ⁵-phosphanone