6,7-diphenyl-1H-pteridine-2,4-dione

Base Information

• Chemical Name: 6,7-diphenyl-1H-pteridine-2,4-dione
• CAS No.: 14892-98-9
• Molecular Formula: C18H12N4O2
• Molecular Weight: 316.319
• DSSTox Substance ID: DTXSID20419978
• Nikkaji Number: J750.229J
• Mol file: 14892-98-9.mol

Synonyms:6,7-diphenyl-1H-pteridine-2,4-dione;14892-98-9;2,4(1H,3H)-Pteridinedione, 6,7-diphenyl-;AC1NTFCY;6,7-Diphenyllumazine;SCHEMBL3533590;SCHEMBL10979871;DTXSID20419978

Chemical Property of 6,7-diphenyl-1H-pteridine-2,4-dione

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 316.09602564
• Heavy Atom Count: 24
• Complexity: 485

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC3=C(NC(=O)NC3=O)N=C2C4=CC=CC=C4

Technology Process of 6,7-diphenyl-1H-pteridine-2,4-dione

There total 10 articles about 6,7-diphenyl-1H-pteridine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

5,6-diaminouracil sulfate (42965-55-9) + benzil (134-81-6) → 6,7-diphenylpteridine-2,4(1H,3H)-dione (14892-98-9)

Guidance literature:

5,6-diaminouracil sulfate; With sodium hydroxide; In methanol; water; at 90 ℃; for 0.25h;

benzil; In tetrahydrofuran; water; at 90 ℃; for 0.75h;

DOI:10.3390/molecules23092271

Reference yield:

5,6-diaminouracil (3240-72-0) + benzil (134-81-6) → 6,7-diphenylpteridine-2,4(1H,3H)-dione (14892-98-9)

Guidance literature:

With ammonia;

DOI:10.1021/ja01221a032

Reference yield:

6,7-diphenyl-1,2-dihydro-2-thioxopteridin-4(3H)-one (14892-97-8) → 6,7-diphenylpteridine-2,4(1H,3H)-dione (14892-98-9)

Guidance literature:

With sodium hydroxide; dihydrogen peroxide;

upstream raw materials:

5,6-diaminouracil

benzil

6,7-diphenyl-1,2-dihydro-2-thioxopteridin-4(3H)-one

8-(2-Acetoxyethyl)-6,7-diphenyllumazin

Downstream raw materials:

3-amino-5,6-diphenyl-pyrazine-2-carboxylic acid butylamide

3-amino-5,6-diphenyl-pyrazine-2-carboxylic acid benzylamide

1,3-dibenzylurea

N-benzyl-N'-(3-benzylcarbamoyl-5,6-diphenyl-pyrazin-2-yl)-urea