42965-55-9

Basic information

• Product Name: 5,6-diaminopyrimidine-2,4-diol sulphate
• Synonyms: 5,6-diaminopyrimidine-2,4-diol sulphate;NSC 264289;NSC 3102;NSC 42280;2,4(1H,3H)-PyriMidinedione, 5,6-diaMino-, sulfate (1:1);5,6-Diaminopyrimidine-2,4-(1H,3H)-dione sulphate, 4,5-Diamino-2,6-dihydroxypyrimidine sulphate, 5,6-Diamino-2,4-dioxo-1,2,3,4-tetrahydropyrimidine sulphate;5,6-Diaminouracil sulphate
• CAS NO: 42965-55-9
• Molecular Formula: C₄H₆N₄O₂*H₂O₄S
• Molecular Weight: 240.19452
• EINECS: 256-022-8
• Mol File: 42965-55-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: >330 °C
• Boiling Point: 583.5°Cat760mmHg
• Flash Point: 306.7°C
• Appearance: White to light brown/Powder
• Density: 1.481g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 5,6-diaminopyrimidine-2,4-diol sulphate(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-diaminopyrimidine-2,4-diol sulphate(42965-55-9)
• EPA Substance Registry System: 5,6-diaminopyrimidine-2,4-diol sulphate(42965-55-9)

Safety Data

• Hazardous Substances Data: 42965-55-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C4H6N4O2.H2O4S/c5-1-2(6)7-4(10)8-3(1)9;1-5(2,3)4/h5H2,(H4,6,7,8,9,10);(H2,1,2,3,4)/p-2

Upstream product

• 5442-24-0 6-amino-5-nitrosouracil 

Downstream Products

• 5807-13-6 1,3,6,8-tetrahydro-2,4,5,7-pyrimido<5,4-g>pteridinetetrone 
• 2577-35-7 5,6-Dihydro-6-oxolumazin 
• 50996-21-9 7-phenyl-2,4(1H,3H)-pteridinedione 
• 50996-22-0 6-phenyl-lumazine 
• 109187-20-4 6-vanillyl-1H,8H-pteridine-2,4,7-trione 
• 1468-26-4 8-azaxanthine 
• 69-89-6 xanthin 
• 31053-46-0 6-Methyl-7-oxo-7,8-dihydrolumazin 
• 14868-37-2 7-methyl-2,4,6(1H,3H,5H)-pteridinetrione 
• 5774-32-3 6,7-dimethyllumazine 
• 69-93-2 uric Acid 
• 13401-38-2 7-methyl-1H-pteridine-2,4-dione 
• 7698-95-5 4.6-Dioxo-pyrimidin<2.1.3>selendiazol 
• 70404-29-4 N-(6-amino-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N'-benzylthiourea 

Relevant articles and documents

Synthesis of purine antiviral agents, hypoxanthine and 6-mercaptopurine

Some potentially biologically active 6-substituted purine derivatives have been synthesized from simple organic reagents. The reaction of urea with ethyl cyanoacetate gave 6-aminopyrimidine-2,4-dione which was converted in two steps into purine derivative, xanthine. The latter was treated with formamide at 200°C to obtain hypoxanthine. The chlorination of hypoxanthine with POCl3 gave 6-chloropurine which was converted into 6-mercaptopurine via reaction with thiourea in acetonitrile, followed by treatment with boiling ethanol.