4-[[[2-[[[2-Oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]phenyl]amino]sulfonyl]phenyl 2,2-dimethylpropanoate

Base Information

Chemical Name:4-[[[2-[[[2-Oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]phenyl]amino]sulfonyl]phenyl 2,2-dimethylpropanoate
CAS No.:150374-98-4
Molecular Formula:C27H28N2O7S
Molecular Weight:524.595
Hs Code.:
DSSTox Substance ID:DTXSID001110814

Synonyms:150374-98-4;SCHEMBL7311912;DTXSID001110814;4-[[[2-[[[2-Oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]phenyl]amino]sulfonyl]phenyl 2,2-dimethylpropanoate;4-(N-(2-((2-(Benzyloxy)-2-oxoethyl)carbamoyl)phenyl)sulfamoyl)phenyl pivalate

Suppliers and Price of 4-[[[2-[[[2-Oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]phenyl]amino]sulfonyl]phenyl 2,2-dimethylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4-[[[2-[[[2-Oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]phenyl]amino]sulfonyl]phenyl 2,2-dimethylpropanoate

Chemical Property:

XLogP3:4.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:12
Exact Mass:524.16172241
Heavy Atom Count:37
Complexity:879

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)OCC3=CC=CC=C3

Technology Process of 4-[[[2-[[[2-Oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]phenyl]amino]sulfonyl]phenyl 2,2-dimethylpropanoate

There total 8 articles about 4-[[[2-[[[2-Oxo-2-(phenylmethoxy)ethyl]amino]carbonyl]phenyl]amino]sulfonyl]phenyl 2,2-dimethylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.5%

: 150374-99-5
p-pivaloyloxybenzenesulfonyl chloride

: benzyl 2-(2-aminobenzamido)acetate

: 150374-98-4
4-(N-(2-(2-(benzyloxy)-2-oxoethylcarbamoyl)phenyl)sulfamoyl)phenylpivalic acid

Guidance literature:: With pyridine; In dichloromethane; at 20 - 25 ℃; for 3.5h; Temperature;

Reference yield:

: 825-90-1
sodium p-hydroxybenzenesulfonate

: 150374-98-4
4-(N-(2-(2-(benzyloxy)-2-oxoethylcarbamoyl)phenyl)sulfamoyl)phenylpivalic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / NaOH / tetrahydrofuran; H₂O / 1 h / 25 °C

2: 86 percent / SOCl₂ / dimethylformamide / 0.5 h / 25 °C

3: pyridine / 1 h / 25 °C

With pyridine; sodium hydroxide; thionyl chloride; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(96)00216-7

Reference yield:

: p-pivaloyloxybenzenesulfonic acid sodium salt

: 150374-98-4
4-(N-(2-(2-(benzyloxy)-2-oxoethylcarbamoyl)phenyl)sulfamoyl)phenylpivalic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / SOCl₂ / dimethylformamide / 0.5 h / 25 °C

2: pyridine / 1 h / 25 °C

With pyridine; thionyl chloride; In N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(96)00216-7