Benzenemethanamine, N-(4-chlorophenyl)-N-(phenylmethyl)-

Base Information

• Chemical Name: Benzenemethanamine, N-(4-chlorophenyl)-N-(phenylmethyl)-
• CAS No.: 15429-21-7
• Molecular Formula: C20H18ClN
• Molecular Weight: 307.823
• DSSTox Substance ID: DTXSID00457393
• Nikkaji Number: J781.112H
• Wikidata: Q82280231
• Mol file: 15429-21-7.mol

Synonyms:4-chloro-n,n-dibenzylaniline;n,n-dibenzyl-4-chloroaniline;15429-21-7;SCHEMBL3031155;Benzenemethanamine, N-(4-chlorophenyl)-N-(phenylmethyl)-;DTXSID00457393;ADAL1289488

Chemical Property of Benzenemethanamine, N-(4-chlorophenyl)-N-(phenylmethyl)-

Chemical Property:

• XLogP3: 5.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 307.1127773
• Heavy Atom Count: 22
• Complexity: 279

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CN(CC2=CC=CC=C2)C3=CC=C(C=C3)Cl

Technology Process of Benzenemethanamine, N-(4-chlorophenyl)-N-(phenylmethyl)-

There total 22 articles about Benzenemethanamine, N-(4-chlorophenyl)-N-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

benzyl chloride (100-44-7) + 4-chloro-aniline (106-47-8) → N,N-dibenzyl-(4-chlorophenyl)amine (15429-21-7)

Guidance literature:

With silica copper(I) oxide; tetrabutylammomium bromide; potassium carbonate; In water; at 100 ℃; for 11h; Green chemistry;

DOI:10.1016/S1872-2067(14)60009-7

Reference yield: 93.0%

benzyl bromide (100-39-0) + 4-chloro-aniline (106-47-8) → N,N-dibenzyl-(4-chlorophenyl)amine (15429-21-7)

Guidance literature:

With hexamethylenetetramine-functionalized silica-coated magnetic nano-Fe₃O₄ core-shell nanocatalyst; In ethanol; at 60 ℃; for 4h;

DOI:10.1016/j.molstruc.2020.128583

Reference yield: 93.0%

2-(4-chloro-phenyl)-5,5-dimethyl-[1,3,2]dioxaborinane (827605-29-8) + N,N-dibenzyl-O-benzoylhydroxylamine (52742-32-2) → N,N-dibenzyl-(4-chlorophenyl)amine (15429-21-7)

Guidance literature:

With o-phenylenebis(diphenylphosphine); copper(II) acetate monohydrate; lithium tert-butoxide; In tetrahydrofuran; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1002/anie.201108773

upstream raw materials:

4-chloro-aniline

benzyl alcohol

benzyl chloride

benzyl bromide

Downstream raw materials:

N-(4-chlorophenyl)benzamide

4-(N,N-dibenzylamino)phenylboronic acid cyclic trimer

N,N-dibenzylaniline

N-Benzylaniline