3-Cyclohexene-1-carboxaldehyde, 4-methyl-, (1R)-

Base Information

• Chemical Name: 3-Cyclohexene-1-carboxaldehyde, 4-methyl-, (1R)-
• CAS No.: 155156-86-8
• Molecular Formula: C8H12O
• Molecular Weight: 124.183
• Mol file: 155156-86-8.mol

Synonyms:(R)-4-methyl-3-cyclohexene-1-carbaldehyde;(R)-4-methylcyclohex-3-ene-carbaldehyde;3-Cyclohexene-1-carboxaldehyde,4-methyl-,(1R);(1R)-4-methyl-3-cyclohexene-1-carboxaldehyde;

Chemical Property of 3-Cyclohexene-1-carboxaldehyde, 4-methyl-, (1R)-

Chemical Property:

• Boiling Point: 176.1±29.0 °C(Predicted)
• PSA: 17.07000
• Density: 0.998±0.06 g/cm3(Predicted)
• LogP: 1.93170

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Cyclohexene-1-carboxaldehyde, 4-methyl-, (1R)-

There total 2 articles about 3-Cyclohexene-1-carboxaldehyde, 4-methyl-, (1R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

acrolein (107-02-8,25068-14-8) + isoprene (78-79-5,9003-31-0) → (1R)-4-methyl-3-cyclohexene-1-carboxaldehyde (155156-86-8)

Guidance literature:

With [bis[3,5-bis(trifluoromethyl)phenyl]-[(2S)-pyrrolidin-1-ium-2-yl]methoxy]trimethylsilane perchlorate; In water; at 4 ℃; for 36h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1002/anie.200801408

Reference yield:

acrolein (107-02-8,25068-14-8) + isoprene (78-79-5,9003-31-0) → (1S)-4-methyl-3-cyclohexene-1-carboxaldehyde (155156-87-9) + (1R)-4-methyl-3-cyclohexene-1-carboxaldehyde (155156-86-8)

Guidance literature:

With (5R)-(+)-2,2,3-trimethyl-5-benzyl-4-imidazolidinone monohydrochloride; at 23 ℃; Title compound not separated from byproducts;

DOI:10.1021/ja000092s

Reference yield:

ethylmagnesium bromide (925-90-6) + (1R)-4-methyl-3-cyclohexene-1-carboxaldehyde (155156-86-8) → 1-[(1R)-4-methylcyclohex-3-en-1-yl]propan-1-one

Guidance literature:

With tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide;

DOI:10.1021/ja017641u

upstream raw materials:

acrolein

isoprene

Downstream raw materials:

(+)-(1R)-4-methyl-cyclohex-3-enecarboxylic acid