Stilbene-4-carbonitrile

Base Information

• Chemical Name: Stilbene-4-carbonitrile
• CAS No.: 1552-58-5
• Molecular Formula: C₁₅H₁₁N
• Molecular Weight: 205.259
• Mol file: 1552-58-5.mol

Synonyms:CNSB;4-cyano-stilbene;

Chemical Property of Stilbene-4-carbonitrile

Chemical Property:

• PSA: 23.79000
• LogP: 3.72868

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Stilbene-4-carbonitrile

There total 56 articles about Stilbene-4-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 4-Cyanochlorobenzene (623-03-0) → 4-cyanostilbene (13041-79-7,14064-68-7,68331-40-8,144606-12-2,1552-58-5,130059-93-7)

Guidance literature:

With tetrabutylammomium bromide; sodium acetate; C₂₇H₂₁FN₄O₂Pd; at 140 ℃; for 2h; Schlenk technique; Inert atmosphere;

DOI:10.1002/ejic.202000530

Reference yield: 99.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 4-iodobenzonitrile (3058-39-7) → 4-cyanostilbene (13041-79-7,14064-68-7,68331-40-8,144606-12-2,1552-58-5,130059-93-7)

Guidance literature:

With tetrabutylammomium bromide; triethylamine; In N,N-dimethyl-formamide; at 120 ℃; for 10h;

DOI:10.1021/acs.inorgchem.7b03271

Reference yield: 98.0%

4-(2-phenylethynyl)benzonitrile (29822-79-5) → (Z)-4-cyanostilbene (1552-58-5,13041-79-7,68331-40-8,130059-93-7,144606-12-2,14064-68-7)

Guidance literature:

With dmap; formic acid; Au₉₉₂₄Ag_0.76; In N,N-dimethyl-formamide; at 70 ℃; for 4h; stereoselective reaction; Inert atmosphere; Green chemistry;

DOI:10.1021/jo502313d

upstream raw materials:

styrene

4-bromobenzenecarbonitrile

acetic acid

4-Cyanochlorobenzene

Downstream raw materials:

p-cyanobenzophenone

(E)-1-cyano-4-styryl-benzene

1-(4-cyanophenyl)-2-phenylethane

4-((Z)-Styryl)-benzonitrile