6-Methyl-2-(methylamino)nicotinic acid

Base Information

• Chemical Name: 6-Methyl-2-(methylamino)nicotinic acid
• CAS No.: 155790-12-8
• Molecular Formula: C8H10N2O2
• Molecular Weight: 166.17700
• Hs Code.: 2933399990
• DSSTox Substance ID: DTXSID60565605
• Mol file: 155790-12-8.mol

Synonyms:6-methyl-2-(methylamino)nicotinic acid;155790-12-8;6-Methyl-2-(Methylamino)Pyridine-3-Carboxylic Acid;6-methyl-2-(methylamino)nicotinicacid;3-Pyridinecarboxylic acid, 6-methyl-2-(methylamino)-;SCHEMBL1758986;DTXSID60565605;2-Methylamine-6-methylnicotinic acid;6-Methyl-2-methylaminonicotinic acid;MFCD04038975;AKOS008105076;CS-0216310;EN300-39490;G33764;A809681

Chemical Property of 6-Methyl-2-(methylamino)nicotinic acid

Chemical Property:

• PSA: 62.22000
• LogP: 1.20290
• Storage Temp.: 2-8°C
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 166.074227566
• Heavy Atom Count: 12
• Complexity: 172

Purity/Quality:

97% ^*data from raw suppliers

6-Methyl-2-(methylamino)pyridine-3-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC(=C(C=C1)C(=O)O)NC

Technology Process of 6-Methyl-2-(methylamino)nicotinic acid

There total 2 articles about 6-Methyl-2-(methylamino)nicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-chloro-6-methyl nicotinic acid (30529-70-5) + methylamine (74-89-5) → 6-methyl-2-methylamino-3-pyridinecarboxylic acid (155790-12-8)

Guidance literature:

In ethanol; at 120 ℃; for 6h;

Reference yield:

→ 6-methyl-2-methylamino-3-pyridinecarboxylic acid (155790-12-8)

Guidance literature:

upstream raw materials:

2-chloro-6-methyl nicotinic acid

methylamine