Technology Process of Palladium, [(2,3-h)-dimethyl 2-butynedioate]bis(triphenylphosphine)-
There total 2 articles about Palladium, [(2,3-h)-dimethyl 2-butynedioate]bis(triphenylphosphine)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
In
tetrahydrofuran;
addn. of (Ph3P)2Pd to a soln. of MeO2CCCCO2Me in THF (room temp., under Ar), stirring (30 min); removing of solvent (reduced pressure), crystn. (THF/pentane), recrystn. (CH2Cl2/MeOH);
DOI:10.1016/0022-328X(89)85347-1
- Guidance literature:
-
In
tetrahydrofuran; toluene;
byproducts: CH2CH2; (Ar); equimolar amts.; dissolving the Pd-complex at -30°C in toluene; dropwise addn. of the acetylene compound soln. (in THF) with stirring at this temp.; stirring for 45 min; filtration over silica gel; addn. of hexane to the filtrate; filtation over silica gel; crystn. at -10°C (several hours); recrystn. from THF/hexane or ether/THF; elem. anal.;
- Guidance literature:
-
In
acetone;
introduction of SO2 into soln. of Pd complex in acetone, 0.5 h; stirring 2 d, SO2 atmosphere; pptn.; washing (n-hexane), drying (vac.); elem. anal.;
