4H-Pyrano[3,4-d]isoxazol-4-one, 3-(2,6-dichlorophenyl)-6,7-dihydro-

Base Information

Chemical Name:4H-Pyrano[3,4-d]isoxazol-4-one, 3-(2,6-dichlorophenyl)-6,7-dihydro-
CAS No.:156496-83-2
Molecular Formula:C12H7Cl2NO3
Molecular Weight:284.098
Hs Code.:
DSSTox Substance ID:DTXSID30452735
Nikkaji Number:J1.541.072H

Synonyms:156496-83-2;3-(2,6-Dichlorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]isoxazol-4-one;4H-Pyrano[3,4-d]isoxazol-4-one, 3-(2,6-dichlorophenyl)-6,7-dihydro-;DTXSID30452735;3-(2,6-Dichlorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]isoxazole-4-one

Suppliers and Price of 4H-Pyrano[3,4-d]isoxazol-4-one, 3-(2,6-dichlorophenyl)-6,7-dihydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4H-Pyrano[3,4-d]isoxazol-4-one, 3-(2,6-dichlorophenyl)-6,7-dihydro-

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:282.9802985
Heavy Atom Count:18
Complexity:331

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(=O)C2=C1ON=C2C3=C(C=CC=C3Cl)Cl

Technology Process of 4H-Pyrano[3,4-d]isoxazol-4-one, 3-(2,6-dichlorophenyl)-6,7-dihydro-

There total 4 articles about 4H-Pyrano[3,4-d]isoxazol-4-one, 3-(2,6-dichlorophenyl)-6,7-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 156496-88-7
cis-3-(2,6-Dichlorophenyl)-3a,6,7,7a-tetrahydro-4H-pyrano[3,4-d]isoxazol-4-one

: 156496-83-2
3-(2,6-Dichlorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]isoxazol-4-one

Guidance literature:: With nickel(IV) oxide; In benzene; for 14h; Heating;
DOI:10.1016/S0040-4039(00)73248-5

Reference yield:

: 3393-45-1
5,6-dihydro-pyran-2-one

: 156496-83-2
3-(2,6-Dichlorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]isoxazol-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / NEt₃ / tetrahydrofuran / 4 h / 20 - 67 °C

2: 65 percent / γ-MnO2 / benzene / Heating

With manganese(IV) oxide; triethylamine; In tetrahydrofuran; benzene;
DOI:10.1039/b008081k

Reference yield:

: 2,6-dichlorobenzohydroximinoyl chloride

: 156496-83-2
3-(2,6-Dichlorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]isoxazol-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / triethyl amine / tetrahydrofuran / r.t., 1 h; reflux, 3 h

2: 69 percent / nickel peroxide / benzene / 14 h / Heating

With nickel(IV) oxide; triethylamine; In tetrahydrofuran; benzene;
DOI:10.1016/S0040-4039(00)73248-5