Methyl 2-(bromomethyl)-4-fluorobenzoate

Base Information

Chemical Name:Methyl 2-(bromomethyl)-4-fluorobenzoate
CAS No.:157652-28-3
Molecular Formula:C9H8BrFO2
Molecular Weight:247.064
Hs Code.:2916310090
European Community (EC) Number:966-469-7
DSSTox Substance ID:DTXSID60592794
Wikidata:Q82487098
Mol file:157652-28-3.mol

Synonyms:methyl 2-(bromomethyl)-4-fluorobenzoate;157652-28-3;METHYL 2-BROMOMETHYL-4-FLUORO-BENZOATE;MFCD11505951;BENZOIC ACID, 2-(BROMOMETHYL)-4-FLUORO-, METHYL ESTER;2-Bromomethyl-4-fluoro-benzoic acid methyl ester;SCHEMBL7703503;DTXSID60592794;DAYFMDZWYCRYEJ-UHFFFAOYSA-N;Methyl 2-bromomethyl-4-fluorobenzoate;AKOS024262450;AB64116;Methyl 2-(bromomethyl)4-fluorobenzoate;Methyl2-(Bromomethyl)-4-fluorobenzoate;AS-42401;SY249653;DB-064179;EN300-133684;A883483

Suppliers and Price of Methyl 2-(bromomethyl)-4-fluorobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Methyl 2-(bromomethyl)-4-fluorobenzoate 97%
250 mg
$ 128.00

SynQuest Laboratories
Methyl 2-(bromomethyl)-4-fluorobenzoate 97%
1 g
$ 320.00

SynQuest Laboratories
Methyl 2-(bromomethyl)-4-fluorobenzoate 97%
5 g
$ 1024.00

Matrix Scientific
Methyl2-(bromomethyl)-4-fluorobenzoate 97%
5g
$ 1797.00

Matrix Scientific
Methyl2-(bromomethyl)-4-fluorobenzoate 97%
1g
$ 630.00

J&W Pharmlab
Methyl2-bromomethyl-4-fluoro-benzoate 97%
50mg
$ 98.00

J&W Pharmlab
Methyl2-bromomethyl-4-fluoro-benzoate 97%
500mg
$ 193.00

J&W Pharmlab
Methyl2-bromomethyl-4-fluoro-benzoate 97%
1g
$ 185.00

J&W Pharmlab
Methyl2-bromomethyl-4-fluoro-benzoate 97%
250mg
$ 148.00

J&W Pharmlab
Methyl2-bromomethyl-4-fluoro-benzoate 97%
100mg
$ 125.00

Total 14 raw suppliers

Chemical Property of Methyl 2-(bromomethyl)-4-fluorobenzoate

Chemical Property:

Vapor Pressure:0.00193mmHg at 25°C
Boiling Point:291.6oC at 760 mmHg
Flash Point:130.1oC
PSA：26.30000
Density:1.534g/cm3
LogP:2.50720
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:245.96917
Heavy Atom Count:13
Complexity:187

Purity/Quality:

97% ^*data from raw suppliers

Methyl 2-(bromomethyl)-4-fluorobenzoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(C=C(C=C1)F)CBr

Technology Process of Methyl 2-(bromomethyl)-4-fluorobenzoate

There total 3 articles about Methyl 2-(bromomethyl)-4-fluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 174403-69-1
4-fluoro-2-methyl benzoic acid methyl ester

: 157652-28-3
2-bromomethyl-4-fluoro-benzoic acid methyl ester

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane;

Reference yield:

: 21900-43-6
4-fluoro-2-methylbenzoyl chloride

: 157652-28-3
2-bromomethyl-4-fluoro-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 20 °C / Cooling with ice

2: N-Bromosuccinimide; dibenzoyl peroxide / 1,2-dichloro-ethane / 8 h / 80 °C

With N-Bromosuccinimide; dibenzoyl peroxide; In 1,2-dichloro-ethane;

Reference yield:

: 321-21-1
4-fluoro-2-methylbenzoic acid

: 157652-28-3
2-bromomethyl-4-fluoro-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 16 h / 0 - 20 °C / Inert atmosphere

2: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 3 h / Inert atmosphere; Reflux

With N-Bromosuccinimide; thionyl chloride; dibenzoyl peroxide; In tetrachloromethane;