3,6-Dichloro-2-nitroaniline

Base Information

• Chemical Name: 3,6-Dichloro-2-nitroaniline
• CAS No.: 15944-74-8
• Molecular Formula: C6H4Cl2N2O2
• Molecular Weight: 207.016
• DSSTox Substance ID: DTXSID60393804
• Wikidata: Q82192763
• Mol file: 15944-74-8.mol

Synonyms:3,6-dichloro-2-nitroaniline;15944-74-8;Benzenamine, 3,6-dichloro-2-nitro-;SCHEMBL11881928;DTXSID60393804;STL195605;AKOS005149640;CS-0359695

Chemical Property of 3,6-Dichloro-2-nitroaniline

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 205.9649828
• Heavy Atom Count: 12
• Complexity: 185

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1Cl)N)[N+](=O)[O-])Cl

Technology Process of 3,6-Dichloro-2-nitroaniline

There total 9 articles about 3,6-Dichloro-2-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dichloroacetanilide (2621-62-7) → 2,5-dchloro-4-nitroacetanilide (38411-17-5) + 3,6-dichloro-2-nitro-aniline (15944-74-8)

Guidance literature:

With nitric acid; Trennung durch Auskochen mit Benzol und Zersetzung mit konz.Schwefelsaeure;

Reference yield:

1,4-dichloro-2,3-dinitrobenzene (65036-57-9) → 3,6-dichloro-2-nitro-aniline (15944-74-8)

Guidance literature:

With ammonia; at 50 - 60 ℃;

Reference yield:

2,5-dichloronitrobenzene (89-61-2) → 3,6-dichloro-2-nitro-aniline (15944-74-8)

Guidance literature:

Multi-step reaction with 2 steps

1: HNO₃+H₂SO₄

2: alcohol; ammonia / 150 - 160 °C

With ethanol; sulfuric acid; ammonia; nitric acid;

upstream raw materials:

2,5-dichloroacetanilide

1,4-dichloro-2,3-dinitrobenzene

ammonia

para-dichlorobenzene

Downstream raw materials:

1,2,3,4,-tetrachlorobenzene

3,6-dichloro-1,2-phenylenediamine

1,2,4-trichloro-3-nitrobenzene

1,4-dichloro-2-iodo-3-nitro-benzene