1,4-Bis(4-methoxyphenyl)butane-1,4-dione

Base Information

• Chemical Name: 1,4-Bis(4-methoxyphenyl)butane-1,4-dione
• CAS No.: 15982-64-6
• Molecular Formula: C18H18O4
• Molecular Weight: 298.339
• Hs Code.: 2914509090
• Mol file: 15982-64-6.mol

Synonyms:1,4-Bis-(4-methoxy-phenyl)-butan-1,4-dion;1,4-bis-(4-methoxy-phenyl)-butane-1,4-dione;1,4-Bis(4-methoxyphenyl)-1,4-butanedione;1,4-Butanedione,1,4-bis(4-methoxyphenyl);1,2-di-p-methylbenzoylethane;1,4-di(p-methoxyphenyl)butan-1,4-dione;

Chemical Property of 1,4-Bis(4-methoxyphenyl)butane-1,4-dione

Chemical Property:

• PSA: 52.60000
• LogP: 3.54960

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,4-Bis(4-methoxyphenyl)butane-1,4-dione

There total 43 articles about 1,4-Bis(4-methoxyphenyl)butane-1,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

PVS (5535-48-8) + 4-methoxy-benzaldehyde (123-11-5) → 1,4-bis(4-methoxyphenyl)butane-1,4-dione (15982-64-6) + 1-(4-methoxyphenyl)-3-(phenylsulfonyl)propan-1-one

Guidance literature:

With 3-(2,4,6-trimethyl-phenyl)-5,6,7,8-tetrahydro-4H-cycloheptathiazol-3-ium perchlorate; potassium tert-butylate; In 1,4-dioxane; at 30 - 70 ℃; for 30.75h; Inert atmosphere;

DOI:10.1021/ol301045x

Reference yield: 82.0%

bis((1-(4-methoxyphenyl)vinyl)oxy)dimethylsilane (1638623-74-1) → 1,4-bis(4-methoxyphenyl)butane-1,4-dione (15982-64-6)

Guidance literature:

With [bis(acetoxy)iodo]benzene; boron trifluoride diethyl etherate; In acetonitrile; at -10 - 20 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.201400405

Reference yield: 82.0%

1,5-di(p-methoxyphenyl)-6,7-dioxabicyclo[3.2.2]nonane (157367-58-3) → 1,4-bis(4-methoxyphenyl)butane-1,4-dione (15982-64-6) + 1-(p-methoxyphenyl)oxy-5-(p-methoxyphenyl)-8-oxabicyclo[3.2.1]octane

Guidance literature:

With oxygen; In dichloromethane; for 5h; Irradiation;

DOI:10.1016/S0040-4039(01)01973-6

upstream raw materials:

1,2-dibromo-1,2-di(4-methoxybenzoyl)ethane

methoxybenzene

succinoyl dichloride

1-(4-methoxyphenyl)-2-(methylsulfonyl)-1-ethanone

Downstream raw materials:

2,5-bis-(4-methoxy-phenyl)-hexane-2,5-diol

2,5-Bis-(4-methoxy-phenyl)-2,5-dimethyl-tetrahydro-furan

1,1,4,4-tetrakis-(4-methoxyphenyl)butane-1,4-diol

1,4-bis-(2-methoxy-phenyl)-1,4-bis-(4-methoxy-phenyl)-butane-1,4-diol