3-(Toluene-4-sulfonyloxymethyl)-piperidine-1-carboxylic acid benzyl ester

Base Information

Chemical Name:3-(Toluene-4-sulfonyloxymethyl)-piperidine-1-carboxylic acid benzyl ester
CAS No.:160586-69-6
Molecular Formula:C21H25NO5S
Molecular Weight:403.49200
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50596569
Mol file:160586-69-6.mol

Synonyms:160586-69-6;3-(Toluene-4-sulfonyloxymethyl)-piperidine-1-carboxylic acid benzyl ester;benzyl 3-[(4-methylphenyl)sulfonyloxymethyl]piperidine-1-carboxylate;1-Cbz-3-(tosyloxymethyl)piperidine;benzyl 3-((tosyloxy)methyl)piperidine-1-carboxylate;SCHEMBL7350346;DTXSID50596569;AB91763;AM100319;DB-314725;CS-0447678;F79442;3-(Tosyloxymethyl)-N-(carbobenzyloxy)piperidine;A921879;3-(Toluene-4-sulfonyloxymethyl)-piperidine-1-carboxylicacidbenzylester;3-(Toluene-4-sulfonyloxymethyl)piperidine-1-carboxylic acid benzyl ester;Benzyl 3-{[(4-methylbenzene-1-sulfonyl)oxy]methyl}piperidine-1-carboxylate

Suppliers and Price of 3-(Toluene-4-sulfonyloxymethyl)-piperidine-1-carboxylic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(Toluene-4-sulfonyloxymethyl)-piperidine-1-carboxylicacidbenzylester 95+%
1g
$ 703.00

Chemenu
benzyl3-((tosyloxy)methyl)piperidine-1-carboxylate 95%
1g
$ 593.00

Acrotein
1-Cbz-3-(tosyloxymethyl)piperidine 97%
0.5g
$ 99.00

ACHEMBLOCK
1-Cbz-3-(tosyloxymethyl)piperidine 95%
5G
$ 540.00

ACHEMBLOCK
1-Cbz-3-(tosyloxymethyl)piperidine 95%
1G
$ 200.00

Total 7 raw suppliers

Chemical Property of 3-(Toluene-4-sulfonyloxymethyl)-piperidine-1-carboxylic acid benzyl ester

Chemical Property:

PSA：81.29000
LogP:4.76780
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:403.14534407
Heavy Atom Count:28
Complexity:588

Purity/Quality:

97% ^*data from raw suppliers

3-(Toluene-4-sulfonyloxymethyl)-piperidine-1-carboxylicacidbenzylester 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OCC2CCCN(C2)C(=O)OCC3=CC=CC=C3

Technology Process of 3-(Toluene-4-sulfonyloxymethyl)-piperidine-1-carboxylic acid benzyl ester

There total 3 articles about 3-(Toluene-4-sulfonyloxymethyl)-piperidine-1-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 39945-51-2,160706-61-6
benzyl 3-(hydroxymethyl)-1-piperidinecarboxylate

: 98-59-9
p-toluenesulfonyl chloride

: 160586-69-6
benzyl 3-((tosyloxy)methyl)piperidine-1-carboxylate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 18h;

Reference yield:

: 4606-65-9
3-(hydroxymethy)piperidine

: 160586-69-6
benzyl 3-((tosyloxy)methyl)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / 1,4-dioxane / 0.5 h / 0 - 20 °C

2: dmap; triethylamine / dichloromethane / 18 h / 0 - 20 °C

With dmap; triethylamine; sodium hydroxide; In 1,4-dioxane; dichloromethane;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 160586-69-6
benzyl 3-((tosyloxy)methyl)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / 1,4-dioxane / 0.5 h / 0 - 20 °C

2: dmap; triethylamine / dichloromethane / 18 h / 0 - 20 °C

With dmap; triethylamine; sodium hydroxide; In 1,4-dioxane; dichloromethane;