5-(benzyloxy)-2-hydroxybenzoic acid

Base Information

• Chemical Name: 5-(benzyloxy)-2-hydroxybenzoic acid
• CAS No.: 16094-44-3
• Molecular Formula: C14H12O4
• Molecular Weight: 244.247
• Hs Code.: 2918990090
• Mol file: 16094-44-3.mol

Synonyms:5-(benzyloxy)-2-hydroxybenzoic acid;Benzoic acid,2-hydroxy-5-(phenylmethoxy);

Chemical Property of 5-(benzyloxy)-2-hydroxybenzoic acid

Chemical Property:

• Melting Point: 157 -160°C
• PSA: 66.76000
• LogP: 2.66940
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: Acetonitrile (Slightly), Chloroform (Slightly, Heated)

Purity/Quality:

97% ^*data from raw suppliers

5-Benzyloxy-2-hydroxybenzoic acid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-(Benzyloxy)-2-Hydroxybenzoic Acid is used in the technical process of toner production for developing electrostatic latent images.

Technology Process of 5-(benzyloxy)-2-hydroxybenzoic acid

There total 3 articles about 5-(benzyloxy)-2-hydroxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2,5-dihydroxybenzoic acid. (490-79-9) + benzyl bromide (100-39-0) → 5-(benzyloxy)-2-hydroxybenzoic acid (16094-44-3)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

DOI:10.1002/ejoc.200400535

Reference yield:

2,5-dihydroxybenzoic acid. (490-79-9) + benzyl chloride (100-44-7) → 5-(benzyloxy)-2-hydroxybenzoic acid (16094-44-3)

Guidance literature:

With potassium hydroxide;

DOI:10.1016/S0040-4039(01)92389-5

Reference yield:

→ 5-(benzyloxy)-2-hydroxybenzoic acid (16094-44-3)

Guidance literature:

Gentisinsaeure 1. Benzylbromid, wss. aethanol. NaOH, 3 h Siedetemp. (-> Na-Salz der 2-Hydroxy-5-benzyloxy-benzoesaeure) 2. HCl;

upstream raw materials:

2,5-dihydroxybenzoic acid.

benzyl chloride

benzyl bromide

Downstream raw materials:

3-(benzyloxy)-6-(tert-butyldimethylsilyloxy)-2-formyl-N,N-dimethylbenzamide

5-(benzyloxy)-2-(tert-butyldimethylsilyloxy)-N,N-dimethylbenzamide

C₁₄H₁₁ClO₃

C₄₀H₃₁NO₈