3H-Imidazo[4,5-b]pyridin-5-amine

Base Information

• Chemical Name: 3H-Imidazo[4,5-b]pyridin-5-amine
• CAS No.: 69825-84-9
• Molecular Formula: C₆H₆N₄
• Molecular Weight: 134.14
• Hs Code.: 2933990090
• NSC Number: 289630
• DSSTox Substance ID: DTXSID60391022
• Mol file: 69825-84-9.mol

Synonyms:3H-Imidazo[4,5-b]pyridin-5-amine;69825-84-9;1H-imidazo[4,5-b]pyridin-5-amine;5-Aminoimidazo[4,5-b]pyridine;3H-Imidazo(4,5-b)pyridin-5-amine;SCHEMBL3180578;SCHEMBL15541149;DTXSID60391022;WEJDQDKMUXUQJJ-UHFFFAOYSA-N;MFCD11846337;NSC289630;AKOS006337519;AM86124;NSC 289630;NSC-289630;AS-31473;A9233;CS-0454975;FT-0724035;EN300-2994151

Chemical Property of 3H-Imidazo[4,5-b]pyridin-5-amine

Chemical Property:

• Boiling Point: 484.301 °C at 760 mmHg
• PKA: 8.12±0.40(Predicted)
• Flash Point: 278.435 °C
• PSA: 67.59000
• Density: 1.481 g/cm³
• LogP: 1.12130
• Storage Temp.: 2-8°C
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 134.059246208
• Heavy Atom Count: 10
• Complexity: 127

Purity/Quality:

≥99% ^*data from raw suppliers

3H-Imidazo[4,5-b]pyridin-5-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NC2=C1NC=N2)N

Technology Process of 3H-Imidazo[4,5-b]pyridin-5-amine

There total 3 articles about 3H-Imidazo[4,5-b]pyridin-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(1(3)H-imidazo[4,5-b]pyridin-5-yl)-formamide (120613-71-0) → 1H-imidazo[4,5-b]pyridin-5-amine (69825-84-9)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01173a527

Reference yield:

formic acid (64-18-6) + 2,3,6-Triaminopyridine dihydrochloride (20284-90-6) → 1H-imidazo[4,5-b]pyridin-5-amine (69825-84-9)

Guidance literature:

Reference yield:

5-chloro-1(3)H-imidazo[4,5-b]pyridine; hydrochloride → 1H-imidazo[4,5-b]pyridin-5-amine (69825-84-9)

Guidance literature:

With ammonium hydroxide; copper(II) sulfate;

upstream raw materials:

formic acid

2,3,6-Triaminopyridine dihydrochloride

N-(1⁽³⁾H-imidazo[4,5-b]pyridin-5-yl)-formamide

Downstream raw materials:

1,4-dihydro-imidazo[4,5-b]pyridin-5-one