Phosphinic acid, cyclohexyl-, methyl ester

Base Information

• Chemical Name: Phosphinic acid, cyclohexyl-, methyl ester
• CAS No.: 16196-03-5
• Molecular Formula: C7H15O2P
• Molecular Weight: 162.169
• DSSTox Substance ID: DTXSID20452047
• Wikidata: Q82272405
• Mol file: 16196-03-5.mol

Synonyms:Phosphinic acid, cyclohexyl-, methyl ester;16196-03-5;SCHEMBL20578002;DTXSID20452047

Chemical Property of Phosphinic acid, cyclohexyl-, methyl ester

Chemical Property:

• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 161.07314168
• Heavy Atom Count: 10
• Complexity: 119

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CO[P+](=O)C1CCCCC1

Technology Process of Phosphinic acid, cyclohexyl-, methyl ester

There total 13 articles about Phosphinic acid, cyclohexyl-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

methyl hypophosphite (14684-31-2) + cyclohexene (110-83-8) → O-methyl cyclohexyl hydrogenphosphinate (16196-03-5)

Guidance literature:

With air; triethyl borane; In 1,4-dioxane; at 20 ℃; for 2h;

DOI:10.1021/jo015876i

Reference yield: 60.0%

cyclohexene (110-83-8) + trimethyl orthoformate (149-73-5) → O-methyl cyclohexyl hydrogenphosphinate (16196-03-5)

Guidance literature:

trimethyl orthoformate; for 2h;

cyclohexene; With air; triethyl borane; In 1,4-dioxane; at 20 ℃; for 2h;

DOI:10.1016/j.jorganchem.2004.10.005

Reference yield: 50.0%

3-(trimethoxysilyl)propan-1-amine (13822-56-5) + cyclohexene (110-83-8) → O-methyl cyclohexyl hydrogenphosphinate (16196-03-5)

Guidance literature:

3-(trimethoxysilyl)propan-1-amine; With hypophosphorous acid; trifluoroacetic acid; In acetonitrile; for 2h; Heating;

cyclohexene; With triethyl borane; In hexane; acetonitrile; at 20 ℃; for 2h;

DOI:10.1016/S0022-328X(01)01204-9

upstream raw materials:

methyl hypophosphite

cyclohexene

3-(trimethoxysilyl)propan-1-amine

cyclohexane-1,2-epoxide

Downstream raw materials:

Cyclohexylphosphinsaeure-(3-hydroxy-propylester)

Cyclohexylphosphinsaeure-<3-hydroxy-propylester>-diaethylamid