Carbonic acid, (4,5-dimethoxy-2-nitrophenyl)methyl 4-nitrophenyl ester

Base Information

• Chemical Name: Carbonic acid, (4,5-dimethoxy-2-nitrophenyl)methyl 4-nitrophenyl ester
• CAS No.: 163518-08-9
• Molecular Formula: C16H14N2O9
• Molecular Weight: 378.295
• Mol file: 163518-08-9.mol

Synonyms:p-nitrophenyl 4,5-dimethoxy-2-nitrobenzyl carbonate;4,5-dimethoxy-2-nitrobenzyl (4-nitrophenyl) carbonate;2-nitro-4,5-dimethoxybenzyl-4'-nitrophenylcarbonate;Carbonic acid,(4,5-dimethoxy-2-nitrophenyl)methyl 4-nitrophenyl ester;

Chemical Property of Carbonic acid, (4,5-dimethoxy-2-nitrophenyl)methyl 4-nitrophenyl ester

Chemical Property:

• PSA: 145.63000
• LogP: 4.28220

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbonic acid, (4,5-dimethoxy-2-nitrophenyl)methyl 4-nitrophenyl ester

There total 1 articles about Carbonic acid, (4,5-dimethoxy-2-nitrophenyl)methyl 4-nitrophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

6-nitroveratryl alcohol (1016-58-6) + 4-Nitrophenyl chloroformate (7693-46-1) → 4,5-dimethoxy-2-nitrobenzyl (4-nitrophenyl) carbonate (163518-08-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 1.5h; Inert atmosphere;

DOI:10.1021/acs.biomac.8b01446

Reference yield: 99.0%

3,6-dioxa-1,8-diaminooctane (929-59-9,892154-56-2) + 4,5-dimethoxy-2-nitrobenzyl (4-nitrophenyl) carbonate (163518-08-9) → bis(4,5-dimethoxy-2-nitrobenzyl) ((ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))-di-carbamate

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In acetonitrile; Reflux;

DOI:10.1002/poc.3935

Reference yield: 95.0%

4,5-dimethoxy-2-nitrobenzyl (4-nitrophenyl) carbonate (163518-08-9) + tert-butyl N-methyl-N-<2-(methylamino)ethyl>carbamate (112257-19-9) → C19H29N3O8 (1236141-70-0)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ja102595j

upstream raw materials:

6-nitroveratryl alcohol

4-Nitrophenyl chloroformate

Downstream raw materials:

((CH₃O)2C₆H₂(NO₂)CH₂OCOC₅H₉NCH₂)2CH₂

C₁₉H₂₉N₃O₈

succinimidyl 3-[(4,5-dimethoxy-2-nitrobenzyloxycarbonyl)amino]propanoate

3-[(4,5-dimethoxy-2-nitrobenzyloxycarbonyl)amino]propanoic acid