Carbonic acid, ethyl (2E)-1-methyl-3-phenyl-2-propenyl ester

Base Information

• Chemical Name: Carbonic acid, ethyl (2E)-1-methyl-3-phenyl-2-propenyl ester
• CAS No.: 163807-60-1
• Molecular Formula: C13H16O3
• Molecular Weight: 220.268
• Mol file: 163807-60-1.mol

Synonyms:

Chemical Property of Carbonic acid, ethyl (2E)-1-methyl-3-phenyl-2-propenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbonic acid, ethyl (2E)-1-methyl-3-phenyl-2-propenyl ester

There total 1 articles about Carbonic acid, ethyl (2E)-1-methyl-3-phenyl-2-propenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

ethyl (E)-1-phenylbut-1-en-3-ol (36004-04-3) + chloroformic acid ethyl ester (541-41-3) → ethyl (E)-3-phenyl-1-methylprop-1-enyl carbonate (163807-60-1)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 20 ℃; for 3h;

DOI:10.1039/b106739g

Reference yield: 86.0%

ethyl (E)-3-phenyl-1-methylprop-1-enyl carbonate (163807-60-1) + phenylboronic acid (98-80-6) → (E)-1,3-diphenyl-1-butene (7302-00-3,7614-93-9,79767-68-3,79767-69-4,7302-01-4,180140-70-9)

Guidance literature:

With water; palladium diacetate; triphenylphosphine; In tetrahydrofuran; at 50 ℃; for 24h; stereoselective reaction;

DOI:10.1021/ol203154j

Reference yield: 82.0%

4-methoxy-benzylamine (2393-23-9) + ethyl (E)-3-phenyl-1-methylprop-1-enyl carbonate (163807-60-1) → (E)-N-(4-methoxybenzyl)-4-phenylbut-3-en-2-amine

Guidance literature:

ethyl (E)-3-phenyl-1-methylprop-1-enyl carbonate; With bis(η3-allyl-μ-chloropalladium(II)); 1,2-bis-(diphenylphosphino)ethane; In ethyl acetate; at 40 ℃; for 0.333333h; Inert atmosphere;

4-methoxy-benzylamine; With triethylamine; In ethyl acetate; at 40 ℃; for 18h; Reagent/catalyst; Solvent; Temperature; Catalytic behavior; Inert atmosphere;

DOI:10.1016/j.tetlet.2016.12.049

upstream raw materials:

ethyl (E)-1-phenylbut-1-en-3-ol

chloroformic acid ethyl ester

Downstream raw materials:

methyl (E)-2-(N-benzhydrylideneamino)-5-phenyl-3-methylpent-4-enoate

(E)-dimethyl 2-(4-phenylbut-3-en-2-yl)malonate

dimethyl <1-phenyl-2(E)-butenyl>malonate

dimethyl (1R,2E)-(1-phenylbut-2-en-1-yl)malonate

Refernces