4-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one

Base Information

Chemical Name:4-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
CAS No.:16442-58-3
Molecular Formula:C15H14N2O
Molecular Weight:238.289
Hs Code.:
DSSTox Substance ID:DTXSID40408985
Nikkaji Number:J922.245F
Mol file:16442-58-3.mol

Synonyms:16442-58-3;4-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one;4-PHENYL-1,3,4,5-TETRAHYDRO-1,5-BENZODIAZEPIN-2-ONE;2-phenyl-1,2,3,5-tetrahydro-1,5-benzodiazepin-4-one;4-Phenyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one;Oprea1_694732;SCHEMBL1421037;DTXSID40408985;2H-1,5-Benzodiazepin-2-one, 1,3,4,5-tetrahydro-4-phenyl-;AKOS000160904;AKOS024288113;BS-21647;CS-0205128;EN300-43440;Z316121480;4-phenyl-1,3,4,5-tetrahydro-2h-1,5-benzodiazepine-2-one;4-Phenyl-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one

Suppliers and Price of 4-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 4-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one

Chemical Property:

PSA：44.62000
LogP:3.40510
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:238.110613074
Heavy Atom Count:18
Complexity:299

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(NC2=CC=CC=C2NC1=O)C3=CC=CC=C3

Technology Process of 4-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one

There total 6 articles about 4-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 95-54-5
1,2-diamino-benzene

: 328012-09-5
(E)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-phenylprop-2-en-1-one

: 16442-58-3
4-phenyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one

Guidance literature:: With triethylamine; In tetrahydrofuran; for 1h; Heating;
DOI:10.1055/s-2005-921918

Reference yield: 77.0%

: 16439-95-5
4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one

: 16442-58-3
4-phenyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one

Guidance literature:: With acetic acid; In methanol; at 20 ℃; for 72h;

Reference yield: 44.0%

: 33603-90-6
(2Z)-2-bromo-3-phenyl-2-propenal

: 95-54-5
1,2-diamino-benzene

: 16442-58-3
4-phenyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one

Guidance literature:: With 2-mesityl-2,5,6,7-tetrahydropyrrolo[2,1-c][1,2,4]triazolium chloride; sodium acetate; In dichloromethane; at 20 ℃; Reagent/catalyst; Molecular sieve; Inert atmosphere;
DOI:10.1002/chem.201705050