16439-95-5

Basic information

• Product Name: 4-Phenyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one
• Synonyms: 4-Phenyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one;1,2-Dihydro-4(3H)-phenyl-1,5-benzodiazepin-2-one;4-Phenyl-1H-benzo[b][1,4]diazepin-2(3H)-one
• CAS NO: 16439-95-5
• Molecular Formula: C₁₅H₁₂N₂O
• Molecular Weight: 236.26858
• Mol File: 16439-95-5.mol
• Article Data: 21

Chemical Properties

• Melting Point: 250 °C
• Boiling Point: 433°Cat760mmHg
• Flash Point: 215.7°C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 1.06E-07mmHg at 25°C
• Refractive Index: 1.647
• PKA: 12.72±0.40(Predicted)
• CAS DataBase Reference: 4-Phenyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Phenyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one(16439-95-5)
• EPA Substance Registry System: 4-Phenyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one(16439-95-5)

Safety Data

• Hazardous Substances Data: 16439-95-5(Hazardous Substances Data)

Usage

General Description

4-Phenyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one is a chemical compound with a molecular formula C14H12N2O. It is a cyclic organic compound that belongs to the class of benzodiazepines. Benzodiazepines are known for their sedative and anxiolytic properties, and are often used as pharmaceutical drugs to treat anxiety, insomnia, and other conditions. This particular compound has a phenyl group attached to a benzo[b][1,4]diazepin-2-one ring, giving it specific chemical and pharmacological properties. Its exact uses and effects in biological systems are dependent on its specific structure and interactions with other molecules.

InChI:InChI=1/C15H12N2O/c18-15-10-14(11-6-2-1-3-7-11)16-12-8-4-5-9-13(12)17-15/h1-9H,10H2,(H,17,18)

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 95-54-5 1,2-diamino-benzene 
• 90331-16-1 3-Dimethylaminoformylidene-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one 
• 1076-59-1 3-phenyl-4H-isoxazol-5-one 
• 115749-29-6 phenyl-3 N-(amino-2 phenyl)amino-5 isoxazole 
• 77092-12-7 6-phenyl-2,2-dimethyl-1,3-dioxin-4-one 
• 67259-20-5 2-(4-methyl-1-piperazinyl)-4-phenyl-3H-1,5-benzodiazepine 
• 614-27-7 methyl 3-oxo-3-phenylpropionate 
• 50-01-1 guanidine hydrochloride 
• 66752-03-2 3-bromo-2-oxo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepine 
• 17356-08-0 thiourea 
• 41054-45-9 4-phenyl-1,3-dihydro-2H-1,5-benzodiazepine-2-thione 
• 115749-28-5 hydroxyamino-2 phenyl-4 benzodiazepine-1,5 
• 50850-07-2 2-methylthio-4-phenyl-3H-1,5-benzodiazepine 

Downstream Products

• 16442-58-3 4-phenyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one 
• 877174-58-8 4-benzo[1,3]dioxol-5-yl-5-phenyl-2-thioxo-2,11-dihydro-1H-benzo[b]pyrido[2,3-e][1,4]diazepine-3-carbonitrile 

Relevant articles and documents

Analgesic and antioxidant activities of 4-phenyl-1,5-benzodiazepin-2-one and its long carbon chains derivatives

The aim of this work is to deepen the pharmacological effect of 4-phenyl-1,5-benzodiazepin-2-one derivatives which have a similar structure to nonionic surfactants: 4-phenyl-1,5-benzodiazepin-2-one is the hydrophilic head, and the carbon chain is hydropho

Asymmetric Hydrogenation of Cyclic Imines of Benzoazepines and Benzodiazepines with Chiral, Cationic Ruthenium–Diamine Catalysts

A method for the highly enantioselective hydrogenation of diverse seven-membered N-containing heterocycles, including 2,4-diaryl-3H-benzo[b]azepines, racemic 2,2,4-trisubstituted 2,3-dihydrobenzo[b][1,4]diazepines, and 4-substituted 1H-benzo[b][1,4]diazep

1,5-Benzodiazepin-2-ones: Investigation of a Family of Photoluminescent Materials

Photoluminescent materials, that are now ubiquitous in our everyday life, have particularly attracted the attention of the scientific community these past few years due to potential important applications such as in bioimaging, sensing, or optoelectronics