4-Thiazoleacetic acid

Base Information

Chemical Name:4-Thiazoleacetic acid
CAS No.:7504-44-1
Molecular Formula:C5H5 N O2 S
Molecular Weight:143.166
Hs Code.:2934100090
European Community (EC) Number:809-710-2
NSC Number:400009,38515
UNII:FG2ETP7MCY
DSSTox Substance ID:DTXSID00284702
Wikidata:Q82019778
Mol file:7504-44-1.mol

Synonyms:4-Thiazoleacetic acid;7504-44-1;2-(Thiazol-4-yl)acetic acid;2-(4-Thiazolyl)acetic Acid;2-(1,3-thiazol-4-yl)acetic acid;1,3-thiazol-4-ylacetic acid;1,3-Thiazole-4-ylacetic acid;4-thiazolylacetic acid;MFCD09991935;NSC-38515;NSC-400009;2-(4-Thiazolyl)aceticAcid;4-carboxymethylthiazole;4-thiazole acetic acid;FG2ETP7MCY;thiazol-4-ylacetic acid;SCHEMBL907962;(1,3-thiazol-4-yl)acetic acid;DTXSID00284702;PISMJKGQNDOCGA-UHFFFAOYSA-N;NSC38515;NSC400009;AKOS010504693;AS-31677;SY023095;1,3-Thiazol-4-ylacetic acid, AldrichCPR;CS-0148809;FT-0738733;EN300-244044;A865750;J-503948;Z800222640

Suppliers and Price of 4-Thiazoleacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Thiazolyl)aceticAcid
50mg
$ 45.00

Matrix Scientific
1,3-Thiazol-4-ylacetic acid hydrochloride
500mg
$ 420.00

Matrix Scientific
1,3-Thiazol-4-ylacetic acid hydrochloride
5g
$ 1575.00

Crysdot
2-(Thiazol-4-yl)aceticacid 97%
5g
$ 748.00

Crysdot
2-(Thiazol-4-yl)aceticacid 97%
1g
$ 247.00

Chemenu
2-(thiazol-4-yl)aceticacid 97%
1g
$ 236.00

ChemBridge Corporation
1,3-thiazol-4-ylaceticacid 95%
1 g
$ 140.00

Apolloscientific
(1,3-Thiazol-4-yl)aceticacid 97%
250mg
$ 164.00

Apolloscientific
(1,3-Thiazol-4-yl)aceticacid 97%
1g
$ 314.00

Apolloscientific
(1,3-Thiazol-4-yl)aceticacid 97%
5g
$ 982.00

Total 20 raw suppliers

Chemical Property of 4-Thiazoleacetic acid

Chemical Property:

Vapor Pressure:0.000208mmHg at 25°C
Melting Point:139 °C
Boiling Point:313.7°C at 760 mmHg
PKA:4.07±0.10(Predicted)
Flash Point:143.5°C
PSA：78.43000
Density:1.437g/cm³
LogP:0.77020
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:143.00409958
Heavy Atom Count:9
Complexity:118

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Thiazolyl)aceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(N=CS1)CC(=O)O

Technology Process of 4-Thiazoleacetic acid

There total 5 articles about 4-Thiazoleacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 120155-43-3
thiazol-4-yl acetic acid ethyl ester

: 7504-44-1
thiazol-4-yl acetic acid

Guidance literature:: With potassium hydroxide;
DOI:10.1002/hlca.660280147 DOI:10.1039/jr9460000091

Reference yield:

: 53266-94-7
ethyl 2-amino-1,3-thiazol-4-acetate

: 7504-44-1
thiazol-4-yl acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: NaNO₂; aqueous HNO₃; H₃PO₄ / Behandeln der Reaktionsloesung mit Kupfer und wss. HBr

2: Raney nickel; ethanol; diethylamine / Hydrogenation

3: ethanolic KOH

With potassium hydroxide; ethanol; phosphoric acid; nitric acid; nickel; diethylamine; sodium nitrite;
DOI:10.1002/hlca.660280147

Reference yield:

: 56355-79-4
ethyl 2-(2-bromo-1,3-thiazol-4-yl)acetate

: 7504-44-1
thiazol-4-yl acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Raney nickel; ethanol; diethylamine / Hydrogenation

2: ethanolic KOH

With potassium hydroxide; ethanol; nickel; diethylamine;
DOI:10.1002/hlca.660280147