4-(Fluoromethyl)benzonitrile

Base Information

Chemical Name:4-(Fluoromethyl)benzonitrile
CAS No.:16473-21-5
Molecular Formula:C8H6FN
Molecular Weight:135.141
Hs Code.:
DSSTox Substance ID:DTXSID40519328
Nikkaji Number:J726.769J
Wikidata:Q82382417
Mol file:16473-21-5.mol

Synonyms:4-(Fluoromethyl)benzonitrile;16473-21-5;SCHEMBL10270726;DTXSID40519328

Suppliers and Price of 4-(Fluoromethyl)benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-(Fluoromethyl)benzonitrile

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:135.048427358
Heavy Atom Count:10
Complexity:139

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1CF)C#N

Technology Process of 4-(Fluoromethyl)benzonitrile

There total 14 articles about 4-(Fluoromethyl)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 16473-21-5
1-cyano-4-(fluoromethyl)benzene

Guidance literature:: With potassium fluoride; formic acid; tetramethylammonium fluoride; N,N`-sulfuryldiimidazole; In N,N-dimethyl-formamide; at 20 ℃; for 4h; Inert atmosphere;

Reference yield: 85.0%

: 17201-43-3
4-cyanobenzyl bromide

: 16473-21-5
1-cyano-4-(fluoromethyl)benzene

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 20h; Ambient temperature;
DOI:10.1021/ja971094o

Reference yield: 84.0%

: (4-cyanobenzyl)boronic acid

: 16473-21-5
1-cyano-4-(fluoromethyl)benzene

Guidance literature:: With phosphoric acid; silver nitrate; Selectfluor; In dichloromethane; water; at 50 ℃; for 8h; Schlenk technique; Inert atmosphere;
DOI:10.1021/ja509548z