1-(Fluoromethyl)-4-methoxybenzene

Base Information

Chemical Name:1-(Fluoromethyl)-4-methoxybenzene
CAS No.:16473-39-5
Molecular Formula:C8H9FO
Molecular Weight:140.157
Hs Code.:
DSSTox Substance ID:DTXSID90459341
Nikkaji Number:J1.127.396C
Wikidata:Q82283087
Mol file:16473-39-5.mol

Synonyms:4-methoxybenzyl fluoride

Suppliers and Price of 1-(Fluoromethyl)-4-methoxybenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(Fluoromethyl)-4-methoxybenzene

Chemical Property:

PSA：9.23000
LogP:2.16470
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:140.063743068
Heavy Atom Count:10
Complexity:87.3

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CF

Technology Process of 1-(Fluoromethyl)-4-methoxybenzene

There total 15 articles about 1-(Fluoromethyl)-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: C₁₄H₁₃FO₃S

: 16473-39-5
4-methoxybenzyl fluoride

Guidance literature:: With disodium hydrogenphosphate; sodium amalgam; In tetrahydrofuran; methanol; at -20 ℃; Inert atmosphere;
DOI:10.1002/anie.201412026

Reference yield: 92.0%

: 105-13-5
4-Methoxybenzyl alcohol

: 16473-39-5
4-methoxybenzyl fluoride

Guidance literature:: With potassium 2-(difluoro(trifluoromethoxy)methoxy)-2,2-difluoroacetate; tetramethylammonium fluoride; at 150 ℃; for 5h; Glovebox; Inert atmosphere; Schlenk technique; Sealed tube;
DOI:10.1021/acs.orglett.0c03238

Reference yield: 73.0%

: 824-94-2
p-methoxybenzyl chloride

: 16473-39-5
4-methoxybenzyl fluoride

Guidance literature:: With 1-butyl-3-methyl-3H-imidazol-1-ium fluoride; In neat (no solvent); at 80 ℃; for 0.5h; Microwave irradiation; Green chemistry;
DOI:10.1016/j.tetlet.2013.12.020