4-Chloro-2'-hydroxy-5'-methylchalcone

Base Information

Chemical Name:4-Chloro-2'-hydroxy-5'-methylchalcone
CAS No.:16635-10-2
Molecular Formula:C16H13ClO2
Molecular Weight:272.731
Hs Code.:
DSSTox Substance ID:DTXSID30387856
Mol file:16635-10-2.mol

Synonyms:4-CHLORO-2'-HYDROXY-5'-METHYLCHALCONE;SCHEMBL5085079;DTXSID30387856;AKOS030698107;16635-10-2

Suppliers and Price of 4-Chloro-2'-hydroxy-5'-methylchalcone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-Chloro-2'-hydroxy-5'-methylchalcone

Chemical Property:

XLogP3:4.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:272.0604073
Heavy Atom Count:19
Complexity:332

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)O)C(=O)C=CC2=CC=C(C=C2)Cl

Technology Process of 4-Chloro-2'-hydroxy-5'-methylchalcone

There total 3 articles about 4-Chloro-2'-hydroxy-5'-methylchalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1450-72-2
5-methyl-2-hydroxyacetophenone

: 104-88-1
4-chlorobenzaldehyde

: 16635-10-2
1-(p-chlorophenyl)-3-(2-hydroxy-5-methylphenyl)prop-1-en-3-one

Guidance literature:: With potassium hydroxide; In ethanol; water; at 20 ℃;

Reference yield:

: 106-44-5
p-cresol

: 16635-10-2
1-(p-chlorophenyl)-3-(2-hydroxy-5-methylphenyl)prop-1-en-3-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridine

1.2: 130 °C

2.1: barium(II) hydroxide / ethanol

With pyridine; barium(II) hydroxide; In ethanol;
DOI:10.1111/cbdd.12841