4-amino-N-(3-methylphenyl)benzenesulfonamide

Base Information

• Chemical Name: 4-amino-N-(3-methylphenyl)benzenesulfonamide
• CAS No.: 16803-94-4
• Molecular Formula: C13H14N2O2S
• Molecular Weight: 262.332
• ChEMBL ID: CHEMBL227573
• DSSTox Substance ID: DTXSID301258996
• Mol file: 16803-94-4.mol

Synonyms:4-amino-N-(3-methylphenyl)benzenesulfonamide;16803-94-4;4-Amino-N-(m-tolyl)benzenesulfonamide;4-amino-N-(3-methylphenyl)benzene-1-sulfonamide;CHEMBL227573;SCHEMBL2240551;DTXSID301258996;MFCD01140091;AKOS000151079;SB81684;VS-12683

Chemical Property of 4-amino-N-(3-methylphenyl)benzenesulfonamide

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 262.07759887
• Heavy Atom Count: 18
• Complexity: 356

Purity/Quality:

98%min ^*data from raw suppliers

4-Amino-N-(3-methylphenyl)benzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)NS(=O)(=O)C2=CC=C(C=C2)N

Technology Process of 4-amino-N-(3-methylphenyl)benzenesulfonamide

There total 8 articles about 4-amino-N-(3-methylphenyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.2%

4-nitro-N-(m-tolyl)benzenesulfonamide (16936-94-0) → N-m-methylphenyl-p-aminobenzenesulphonamide (16803-94-4)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; under 760.051 Torr;

DOI:10.1021/acs.jmedchem.0c00932

Reference yield:

1-amino-3-methylbenzene (108-44-1) → N-m-methylphenyl-p-aminobenzenesulphonamide (16803-94-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / pyridine / 20 °C

2: 70 percent / H₂ / Pd/C / ethanol

With pyridine; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/j.bmc.2006.10.029

Reference yield:

4-Nitrobenzenesulfonyl chloride (98-74-8) → N-m-methylphenyl-p-aminobenzenesulphonamide (16803-94-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / pyridine / 20 °C

2: 70 percent / H₂ / Pd/C / ethanol

With pyridine; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/j.bmc.2006.10.029

upstream raw materials:

4-nitro-N-(m-tolyl)benzenesulfonamide

1-amino-3-methylbenzene

4-Nitrobenzenesulfonyl chloride

p-acetylaminobenzenesulfonyl chloride

Downstream raw materials:

4-(8-Hydroxy-quinolin-5-ylazo)-N-m-tolyl-benzenesulfonamide

coumarin-3N-(4'-(N'-m-methylphenyl)sulphonamidophenyl)carboxamide

1,3-dihydro-5-1-(m-tolyl)-p-sulphamylbenzeneazo>-1-(2'-naphthyl)-3-phenyl-2-thioxo-2H,5H-pyrimidine-4,6-dione

1,3-dihydro-5-1-(m-methylphenyl)-p-sulphamylbenzeneazo>-1-(2'-naphthyl)-3-(p-tolyl)-2-thioxo-2H,5H-pyrimidine-4,6-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 16803-94-4 4-amino-N-(3-methylphenyl)benzenesulfonamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send