Acetamide, N-(4-(6-(1-pyrrolidinyl)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenyl)-

Base Information

Chemical Name:Acetamide, N-(4-(6-(1-pyrrolidinyl)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenyl)-
CAS No.:87540-06-5
Molecular Formula:C21H20 N6 O
Molecular Weight:372.4231
Hs Code.:
DSSTox Substance ID:DTXSID10236398
Wikidata:Q83118349
ChEMBL ID:CHEMBL14234

Synonyms:BRN 6443775;Acetamide, N-(4-(6-(1-pyrrolidinyl)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenyl)-;N-(4-(6-(1-Pyrrolidinyl)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenyl)acetamide;87540-06-5;CHEMBL14234;SCHEMBL10665604;DTXSID10236398

Suppliers and Price of Acetamide, N-(4-(6-(1-pyrrolidinyl)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetamide, N-(4-(6-(1-pyrrolidinyl)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenyl)-

Chemical Property:

Density:1.4g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:372.16985928
Heavy Atom Count:28
Complexity:559

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)C2=NN=C3N2N=C(C4=CC=CC=C43)N5CCCC5

Technology Process of Acetamide, N-(4-(6-(1-pyrrolidinyl)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenyl)-

There total 4 articles about Acetamide, N-(4-(6-(1-pyrrolidinyl)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 123-75-1
pyrrolidine

: 113628-52-7
N-[4-(6-Chloro-[1,2,4]triazolo[3,4-a]phthalazin-3-yl)-phenyl]-acetamide

: 87540-06-5
3-(4-acetylaminophenyl)-6-(1-pyrrolidinyl)-1,2,4-triazolo[3,4-a]phthalazine

Guidance literature:: at 140 ℃; for 30h;
DOI:10.1021/jm00401a010

Reference yield:

: 51935-42-3,59275-72-8
1-chloro-4-hydrazinophthalazine

: 87540-06-5
3-(4-acetylaminophenyl)-6-(1-pyrrolidinyl)-1,2,4-triazolo[3,4-a]phthalazine

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / 0.1N HCl / 0.17 h / 60 °C

2: 85 percent / Br₂, sodium acetate / acetic acid / 1 h / Ambient temperature

3: 87 percent / 30 h / 140 °C

With hydrogenchloride; bromine; sodium acetate; In acetic acid;
DOI:10.1021/jm00401a010

Reference yield:

: 122-85-0
para-acetamidobenzaldehyde

: 87540-06-5
3-(4-acetylaminophenyl)-6-(1-pyrrolidinyl)-1,2,4-triazolo[3,4-a]phthalazine

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / 0.1N HCl / 0.17 h / 60 °C

2: 85 percent / Br₂, sodium acetate / acetic acid / 1 h / Ambient temperature

3: 87 percent / 30 h / 140 °C

With hydrogenchloride; bromine; sodium acetate; In acetic acid;
DOI:10.1021/jm00401a010