5-Bromo-2,4-dimethoxyaniline

Base Information

• Chemical Name: 5-Bromo-2,4-dimethoxyaniline
• CAS No.: 169883-36-7
• Molecular Formula: C8H10BrNO2
• Molecular Weight: 232.077
• Hs Code.: 2922299090
• DSSTox Substance ID: DTXSID10603884
• Wikidata: Q82501478
• Mol file: 169883-36-7.mol

Synonyms:5-bromo-2,4-dimethoxyaniline;169883-36-7;Benzenamine, 5-bromo-2,4-dimethoxy-;MFCD14534267;SCHEMBL4896660;DTXSID10603884;MNCWCTCUSSOSKJ-UHFFFAOYSA-N;AKOS016009171;SB80708;AS-10621;DB-095174;EN300-89874;S10834;Z1147474006

Chemical Property of 5-Bromo-2,4-dimethoxyaniline

Chemical Property:

• Boiling Point: 316.5±37.0 °C(Predicted)
• PKA: 4.07±0.10(Predicted)
• PSA: 44.48000
• Density: 1.488±0.06 g/cm3(Predicted)
• LogP: 2.62970
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 230.98949
• Heavy Atom Count: 12
• Complexity: 145

Purity/Quality:

99% ^*data from raw suppliers

5-Bromo-2,4-dimethoxyaniline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1N)Br)OC

Technology Process of 5-Bromo-2,4-dimethoxyaniline

There total 5 articles about 5-Bromo-2,4-dimethoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-bromo-2,4-dimethoxy-5-nitrobenzene (778599-56-7) → 5-bromo 2,4-dimethoxy aniline (169883-36-7)

Guidance literature:

With tin(ll) chloride; In ethanol;

DOI:10.1002/chem.201002491

Reference yield: 23.0%

2,4-Dimethoxyaniline (2735-04-8,161687-55-4) → 5-bromo 2,4-dimethoxy aniline (169883-36-7)

Guidance literature:

With bromine; potassium carbonate; In chloroform; for 4h;

Reference yield: 23.0%

2,4-Dimethoxyaniline (2735-04-8,161687-55-4) → 5-bromo 2,4-dimethoxy aniline (169883-36-7)

Guidance literature:

With bromine; potassium carbonate; In chloroform; for 2h;

upstream raw materials:

2,4-Dimethoxyaniline

2,4-dimethoxynitrobenzene

1-bromo-2,4-dimethoxy-5-nitrobenzene

1,3-Dimethoxybenzene

Downstream raw materials:

1-bromo-5-isocyanato-2,4-dimethoxybenzene

1-azido-5-bromo-2,4-dimethoxybenzene

4,4'-(2,5-dimethoxy-1,4-phenylene)bis(1-(5-bromo-2,4-dimethoxyphenyl)-1H-1,2,3-triazole)