Ethyl 2-chloro-2-(4-methoxyphenyl)acetate

Base Information

Chemical Name:Ethyl 2-chloro-2-(4-methoxyphenyl)acetate
CAS No.:75908-61-1
Molecular Formula:C11H13 Cl O3
Molecular Weight:228.675
Hs Code.:
NSC Number:165802
DSSTox Substance ID:DTXSID00304439

Synonyms:75908-61-1;ethyl 2-chloro-2-(4-methoxyphenyl)acetate;NSC165802;DTXSID00304439;AKOS011508102;NSC-165802

Suppliers and Price of Ethyl 2-chloro-2-(4-methoxyphenyl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethyl 2-chloro-2-(4-methoxyphenyl)acetate

Chemical Property:

Vapor Pressure:0.000719mmHg at 25°C
Boiling Point:307.6°Cat760mmHg
Flash Point:122.7°C
Density:1.173g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:228.0553220
Heavy Atom Count:15
Complexity:200

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C1=CC=C(C=C1)OC)Cl

Technology Process of Ethyl 2-chloro-2-(4-methoxyphenyl)acetate

There total 5 articles about Ethyl 2-chloro-2-(4-methoxyphenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 36141-66-9
ethyl 2-hydroxy-2-(4-methoxyphenyl)acetate

: 75908-61-1
ethyl 4-methoxyphenyl-α-chloroacetate

Guidance literature:: With thionyl chloride; In chloroform; at 20 ℃; for 1h;

Reference yield:

: 75908-61-1
ethyl 4-methoxyphenyl-α-chloroacetate

Guidance literature:: With pyridine; trichlorophosphate;
DOI:10.1021/jo01125a016

Reference yield:

: 20714-90-3
4-Methoxymandelic acid

: 75908-61-1
ethyl 4-methoxyphenyl-α-chloroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / Reflux

2: thionyl chloride / chloroform / 1 h / 20 °C

With thionyl chloride; sulfuric acid; In chloroform;