Ethanethioic acid, S-(4-ethynylphenyl) ester

Base Information

• Chemical Name: Ethanethioic acid, S-(4-ethynylphenyl) ester
• CAS No.: 170159-24-7
• Molecular Formula: C10H8OS
• Molecular Weight: 176.239
• Mol file: 170159-24-7.mol

Synonyms:4-ethynyl-1-acetylsulfanylbenzene;1-(S-acetylthio)-4-ethynylbenzene;S-(4-ethynylphenyl) ethanethioate;1-acetylsulfanyl-4-ethynylbenzene;Thioacetic acid S-(4-ethynyl-phenyl) ester;1-acetylsulfanyl-4-ethynyl-benzene;S-(4-((ethynyl)phenyl))ethanethioate;

Chemical Property of Ethanethioic acid, S-(4-ethynylphenyl) ester

Chemical Property:

• PSA: 42.37000
• LogP: 2.30650

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethanethioic acid, S-(4-ethynylphenyl) ester

There total 13 articles about Ethanethioic acid, S-(4-ethynylphenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-thioacetyl-4-<(trimethylsilyl)ethynyl>benzene (170159-17-8) → acetylsulfanyl-4-(ethynyl)benzene (170159-24-7)

Guidance literature:

With tetrabutyl ammonium fluoride; acetic anhydride; acetic acid; In tetrahydrofuran; at 0 - 20 ℃; for 0.0833333h;

DOI:10.1021/jo962335y

Reference yield: 40.0%

acetyl chloride (75-36-5) + 1-tert-butylsulfanyl-4-(2'-triisopropylsilylethynyl)-benzene (795274-48-5) → S-(4-{1-[(trifluoromethanesulfonyl)oxy]vinyl}phenyl) ethanethioate + acetylsulfanyl-4-(ethynyl)benzene (170159-24-7)

Guidance literature:

With bismuth(lll) trifluoromethanesulfonate; In toluene; acetonitrile; at 20 ℃; for 24h;

DOI:10.1002/ejoc.201500420

Reference yield: 3.0%

acetyl chloride (75-36-5) + 1-(tert-butylsulfanyl)-4-ethynylbenzene (135883-45-3) → acetylsulfanyl-4-(ethynyl)benzene (170159-24-7)

Guidance literature:

With bromine; acetic acid; at 20 ℃;

DOI:10.1039/b408677e

upstream raw materials:

1-thioacetyl-4-<(trimethylsilyl)ethynyl>benzene

acetyl chloride

1-(tert-butylsulfanyl)-4-ethynylbenzene

1-iodo-4-thioacetylbenzene

Downstream raw materials:

thioacetic acid S-[4-(4-trimethylsilanylethynylphenylethynyl)phenyl] ester

Thioacetic acid S-[4-(4-ethyl-5-{4-ethyl-5-[4-ethyl-5-(4-ethyl-5-trimethylsilanylethynyl-thiophen-2-ylethynyl)-thiophen-2-ylethynyl]-thiophen-2-ylethynyl}-thiophen-2-ylethynyl)-phenyl] ester

Thioacetic acid S-[4-(3-dodecyl-4-{3-dodecyl-4-[3-dodecyl-4-(3-dodecyl-4-trimethylsilanylethynyl-phenylethynyl)-phenylethynyl]-phenylethynyl}-phenylethynyl)-phenyl] ester

thioacetic acid S-(4-{4-[bis-[4-(4-acetylsulfanyl-phenylethynyl)-phenyl]-(4-trimethylsilanylethynyl-phenyl)-silanyl]-phenylethynyl}-phenyl) ester