Methyl 5-(4-fluorobenzoyl)furan-2-carboxylate

Base Information

Chemical Name:Methyl 5-(4-fluorobenzoyl)furan-2-carboxylate
CAS No.:170632-16-3
Molecular Formula:C13H9FO4
Molecular Weight:248.20700
Hs Code.:
DSSTox Substance ID:DTXSID80453535
Wikidata:Q82274690
Mol file:170632-16-3.mol

Synonyms:170632-16-3;Methyl 5-(4-fluorobenzoyl)furan-2-carboxylate;SCHEMBL2958453;5-(4-Fluoro-benzoyl)-furan-2-carboxylic acid methyl ester;DTXSID80453535;2-Furancarboxylic acid, 5-(4-fluorobenzoyl)-, methyl ester;AKOS020195143;Methyl5-(4-fluorobenzoyl)furan-2-carboxylate

Suppliers and Price of Methyl 5-(4-fluorobenzoyl)furan-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl5-(4-fluorobenzoyl)furan-2-carboxylate 97%
10g
$ 1637.00

Crysdot
Methyl5-(4-fluorobenzoyl)furan-2-carboxylate 97%
5g
$ 1240.00

Crysdot
Methyl5-(4-fluorobenzoyl)furan-2-carboxylate 97%
1g
$ 446.00

Total 0 raw suppliers

Chemical Property of Methyl 5-(4-fluorobenzoyl)furan-2-carboxylate

Chemical Property:

PSA：56.51000
LogP:2.43630
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:248.04848693
Heavy Atom Count:18
Complexity:323

Purity/Quality:: Methyl5-(4-fluorobenzoyl)furan-2-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=C(O1)C(=O)C2=CC=C(C=C2)F

Technology Process of Methyl 5-(4-fluorobenzoyl)furan-2-carboxylate

There total 2 articles about Methyl 5-(4-fluorobenzoyl)furan-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.1%

: 611-13-2
2-furoic acid methyl ester

: 403-43-0
4-fluorobenzoyl chloride

: 170632-16-3
4'-fluorophenyl 5-methoxycarbonyl-2-furyl ketone

Guidance literature:: With iron(III) chloride; In dichloromethane; for 36h; Heating;
DOI:10.1021/jm020070b

Reference yield:

: 170632-16-3
4'-fluorophenyl 5-methoxycarbonyl-2-furyl ketone

Guidance literature:

Reference yield:

: 170632-16-3
4'-fluorophenyl 5-methoxycarbonyl-2-furyl ketone

: 170632-32-3
1-benzyl-3-(5'-methoxycarbonyl-2'-furyl)-6-fluoroindazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / methanol / Heating

2.1: Pb(OAc)4 / CH₂Cl₂ / 0.5 h / 30 °C

2.2: BF₃*Et₂O / CH₂Cl₂ / 0.5 h / Heating

With lead(IV) acetate; acetic acid; In methanol; dichloromethane;
DOI:10.1021/jm020070b