Fmoc-Gly-Gly-Gly-OH

Base Information

• Chemical Name: Fmoc-Gly-Gly-Gly-OH
• CAS No.: 170941-79-4
• Molecular Formula: C21H21N3O6
• Molecular Weight: 411.40800
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID70427068
• Nikkaji Number: J1.493.537A
• Wikidata: Q72478623
• Mol file: 170941-79-4.mol

Synonyms:Fmoc-Gly-Gly-Gly-OH;170941-79-4;1-(9H-Fluoren-9-yl)-3,6,9-trioxo-2-oxa-4,7,10-triazadodecan-12-oic acid;N-Fmoc-glycylglycylglycine;MFCD00190881;2-[[2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetyl]amino]acetic Acid;2-[2-(2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]-amino}acetamido)acetamido]acetic acid;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylglycylglycine;2-[2-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetamido)acetamido]acetic acid;n-((9h-fluoren-9-ylmethoxy)carbonyl)glycylglycylglycine;FMOC-GLYCYL-GLYCYL-GLYCINE;Fmoc-G3;SCHEMBL14453743;DTXSID70427068;YUYBSGRVYRPYLB-UHFFFAOYSA-N;AMY25391;Glycine, N-[N-[N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycyl]glycyl]-;AKOS015840984;SS-4172;BP-24383;SY038292;CS-0149764;FT-0682642;I10382;EN300-1502448;A881973;J-503477;(((9H-Fluoren-9-yl)methoxy)carbonyl)glycylglycylglycine;N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}glycylglycylglycine;N-[N-[N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycyl]glycyl]-glycine;2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]acetamido}acetic acid

Chemical Property of Fmoc-Gly-Gly-Gly-OH

Chemical Property:

• Boiling Point: 811.8±65.0 °C(Predicted)
• PKA: 3.33±0.10(Predicted)
• PSA: 133.83000
• Density: 1.354±0.06 g/cm3(Predicted)
• LogP: 2.01480
• Storage Temp.: -15°C
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 9
• Exact Mass: 411.14303540
• Heavy Atom Count: 30
• Complexity: 633

Purity/Quality:

97% ^*data from raw suppliers

Fmoc-gly-gly-gly-oh ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCC(=O)NCC(=O)NCC(=O)O

Technology Process of Fmoc-Gly-Gly-Gly-OH

There total 2 articles about Fmoc-Gly-Gly-Gly-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

glycine-glycine-glycine (556-33-2) + (fluorenylmethoxy)carbonyl chloride (28920-43-6) → 9-fluorenylmethoxycarbonyl Gly-Gly-Gly-OH (170941-79-4)

Guidance literature:

With sodium carbonate; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

DOI:10.1002/bip.21612

Reference yield:

→ 9-fluorenylmethoxycarbonyl Gly-Gly-Gly-OH (170941-79-4)

Guidance literature:

Reference yield: 100.0%

9-fluorenylmethoxycarbonyl Gly-Gly-Gly-OH (170941-79-4) + C35H60N6O12 → C56H79N9O17

Guidance literature:

9-fluorenylmethoxycarbonyl Gly-Gly-Gly-OH; With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; for 0.166667h;

C₃₅H₆₀N₆O₁₂; In N,N-dimethyl-formamide; at 20 ℃; for 18.5h;

upstream raw materials:

glycine-glycine-glycine

(fluorenylmethoxy)carbonyl chloride