Tert-butyl 4-nitro-2-iodophenylcarbamate

Base Information

Chemical Name:Tert-butyl 4-nitro-2-iodophenylcarbamate
CAS No.:171513-06-7
Molecular Formula:C11H13IN2O4
Molecular Weight:364.14
Hs Code.:2924299090
DSSTox Substance ID:DTXSID50427763
Nikkaji Number:J1.604.037A
Wikidata:Q82240454
Mol file:171513-06-7.mol

Synonyms:171513-06-7;tert-butyl 4-nitro-2-iodophenylcarbamate;TERT-BUTYL 2-IODO-4-NITROPHENYLCARBAMATE;tert-butyl N-(2-iodo-4-nitrophenyl)carbamate;tert-Butyl (2-iodo-4-nitrophenyl)carbamate;AB3445;SCHEMBL3010106;DTXSID50427763;MCPGEGLMPANJTH-UHFFFAOYSA-N;MFCD04971310;SB83720;tert-Butyl(2-iodo-4-nitrophenyl)carbamate;N-(tert-Butoxycarbonyl)-2-iodo-4-nitroaniline;EN300-5007707;AI-942/42301766

Suppliers and Price of Tert-butyl 4-nitro-2-iodophenylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl(2-iodo-4-nitrophenyl)carbamate 95+%
5g
$ 682.00

American Custom Chemicals Corporation
TERT-BUTYL-2-IODO-4-NITROPHENYLCARBAMATE 95.00%
5MG
$ 500.15

Total 1 raw suppliers

Chemical Property of Tert-butyl 4-nitro-2-iodophenylcarbamate

Chemical Property:

PSA：87.64000
LogP:4.08320
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:363.99200
Heavy Atom Count:18
Complexity:324

Purity/Quality:: tert-Butyl(2-iodo-4-nitrophenyl)carbamate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])I

Technology Process of Tert-butyl 4-nitro-2-iodophenylcarbamate

There total 3 articles about Tert-butyl 4-nitro-2-iodophenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 395639-04-0
bis(1,1-dimethylethyl)(2-iodo-4-nitrophenyl)imidocarbonate

: 171513-06-7
1,1-dimethylethyl (2-iodo-4-nitrophenyl)carbamate

Guidance literature:: With nitric acid; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1016/S0040-4020(01)00900-0

Reference yield: 92.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 6293-83-0
2-iodo-4-nitrophenylamine

: 171513-06-7
1,1-dimethylethyl (2-iodo-4-nitrophenyl)carbamate

Guidance literature:: With dmap; In acetonitrile; at 0 - 65 ℃; for 2.67h;

Reference yield:

: 6293-83-0
2-iodo-4-nitrophenylamine

: 171513-06-7
1,1-dimethylethyl (2-iodo-4-nitrophenyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / tetrahydrofuran / 3 h / Inert atmosphere; Reflux

2: potassium carbonate / methanol / 16 h / Inert atmosphere; Reflux

With dmap; potassium carbonate; In tetrahydrofuran; methanol;
DOI:10.1021/acs.orglett.6b00390