2-Oxazoleethanol, 4,5-dihydro-beta-methyl-

Base Information

• Chemical Name: 2-Oxazoleethanol, 4,5-dihydro-beta-methyl-
• CAS No.: 13670-31-0
• Molecular Formula: C6H11 N O2
• Molecular Weight: 129.15704
• Hs Code.: 2934999090
• European Community (EC) Number: 627-824-9
• DSSTox Substance ID: DTXSID80884628
• Nikkaji Number: J421.892B
• Mol file: 13670-31-0.mol

Synonyms:13670-31-0;2-Oxazoleethanol, 4,5-dihydro-beta-methyl-;2-(4,5-dihydro-1,3-oxazol-2-yl)propan-1-ol;2-(4,5-Dihydrooxazol-2-yl)propan-1-ol;2-Oxazoleethanol, 4,5-dihydro-.beta.-methyl-;2-(1-(Hydroxymethyl)ethyl)-4,5-dihydrooxazole;2-[1-(Hydroxymethyl)ethyl] oxazoline;SCHEMBL1126029;DTXSID80884628;2-(3-hydroxy-2-propyl)-2-oxazoline;2-(alpha-hydroxymethylethyl)-2-oxazoline;4,5-Dihydro-beta-methyl-2-oxazoleethanol;2-(1-(HYDROXYMETHYL)ETHYL)-OXAZOLINE&

Chemical Property of 2-Oxazoleethanol, 4,5-dihydro-beta-methyl-

Chemical Property:

• Vapor Pressure: 0.0449mmHg at 25°C
• Refractive Index: n20/D 1.4800(lit.)
• Boiling Point: 210°Cat760mmHg
• Flash Point: 80.8°C
• PSA: 41.82000
• Density: 1.19g/cm³
• LogP: -0.52090
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 129.078978594
• Heavy Atom Count: 9
• Complexity: 122

Purity/Quality:

99% ^*data from raw suppliers

2-[1-(HYDROXYMETHYL)ETHYL] OXAZOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(CO)C1=NCCO1

Technology Process of 2-Oxazoleethanol, 4,5-dihydro-beta-methyl-

There total 3 articles about 2-Oxazoleethanol, 4,5-dihydro-beta-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2-hydroxyethyl)propionamide (18266-55-2) → 2-(4,5-dihydro-oxazol-2-yl)-propan-1-ol (13670-31-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Al₂O₃ / 320 °C / 10 - 20 Torr

2: Et₃N

With triethylamine; aluminum oxide;

Reference yield:

2-ethyl-4,5-dihydrooxazole (10431-98-8) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → 2-(4,5-dihydro-oxazol-2-yl)-propan-1-ol (13670-31-0)

Guidance literature:

With triethylamine;

Reference yield:

→ 2-(4,5-dihydro-oxazol-2-yl)-propan-1-ol (13670-31-0)

Guidance literature:

Oxazolin IV, kat.Hydrierung;

upstream raw materials:

2-ethyl-4,5-dihydrooxazole

formaldehyd

N-(2-hydroxyethyl)propionamide

Downstream raw materials:

2-(Propen-2-yl)-4,5-dihydro-1,3-oxazole