4-Bromo-5-methoxy-2-nitroaniline

Base Information

Chemical Name:4-Bromo-5-methoxy-2-nitroaniline
CAS No.:173312-36-2
Molecular Formula:C7H7BrN2O3
Molecular Weight:247.048
Hs Code.:2922299090
European Community (EC) Number:804-840-6
DSSTox Substance ID:DTXSID40445113
Nikkaji Number:J2.249.408B
Wikidata:Q82263449
Mol file:173312-36-2.mol

Synonyms:4-BROMO-5-METHOXY-2-NITROANILINE;173312-36-2;4-bromo-5-methoxy-2-nitro-aniline;Benzenamine, 4-bromo-5-methoxy-2-nitro-;SCHEMBL4268905;DTXSID40445113;JYXJPWNTXBYKMD-UHFFFAOYSA-N;2-Nitro-4-bromo-5-methoxyaniline;YGA31236;MFCD13659425;AKOS015835326;CS-0309883;EN300-187994;P19063

Suppliers and Price of 4-Bromo-5-methoxy-2-nitroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Bromo-5-methoxy-2-nitroaniline
1g
$ 165.00

SynQuest Laboratories
4-Bromo-5-methoxy-2-nitroaniline 98%
5 g
$ 472.00

SynQuest Laboratories
4-Bromo-5-methoxy-2-nitroaniline 98%
1 g
$ 144.00

Matrix Scientific
4-Bromo-5-methoxy-2-nitroaniline 95+%
1g
$ 303.00

Matrix Scientific
4-Bromo-5-methoxy-2-nitroaniline 95+%
5g
$ 807.00

Chemcia Scientific
4-Bromo-5-methoxy-2-nitro-phenylamine ＞97%
10 G
$ 650.00

Apolloscientific
4-Bromo-5-methoxy-2-nitroaniline 98%
1g
$ 131.00

Apolloscientific
4-Bromo-5-methoxy-2-nitroaniline 98%
5g
$ 428.00

American Custom Chemicals Corporation
4-BROMO-5-METHOXY-2-NITROANILINE 95.00%
5MG
$ 503.05

Alichem
4-Bromo-5-methoxy-2-nitroaniline
5g
$ 298.76

Total 11 raw suppliers

Chemical Property of 4-Bromo-5-methoxy-2-nitroaniline

Chemical Property:

Boiling Point:368.4±37.0 °C(Predicted)
PKA:-1.44±0.25(Predicted)
PSA：81.07000
Density:1.718±0.06 g/cm3(Predicted)
LogP:3.05250
Storage Temp.:Room temperature.
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:245.96400
Heavy Atom Count:13
Complexity:197

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-5-methoxy-2-nitroaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C(=C1)N)[N+](=O)[O-])Br
Uses 4-Bromo-5-methoxy-2-nitroaniline, is an intermediate in the synthesis of novel benzimidazoles Urea, acting as inhibitors of DNA Gyrase and Topoisomerase IV, possessing potent antibacterial activity.

Technology Process of 4-Bromo-5-methoxy-2-nitroaniline

There total 11 articles about 4-Bromo-5-methoxy-2-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 173312-35-1
4'-bromo-5'-methoxy-2'-nitroacetanilide

: 173312-36-2
4-bromo-5-methoxy-2-nitrobenzeneamine

Guidance literature:: With hydrogenchloride; acetic acid; for 1h; Heating;
DOI:10.1002/jhet.5570320523

Reference yield: 89.0%

: 16133-49-6
5-methoxy-2-nitroaniline

: 173312-36-2
4-bromo-5-methoxy-2-nitrobenzeneamine

Guidance literature:: With N-Bromosuccinimide; In acetonitrile; Inert atmosphere; Reflux;

Reference yield:

: 77337-82-7
1-bromo-2-methoxy-4-nitrobenzene

: 173312-36-2
4-bromo-5-methoxy-2-nitrobenzeneamine

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / 5percent Pd/C / ethyl acetate

3: KNO₃

4: 10percent NaOH / ethanol / Heating

With sodium hydroxide; hydrogen; potassium nitrate; palladium on activated charcoal; In ethanol; ethyl acetate;
DOI:10.1016/0040-4039(95)01562-V