DICYCLOHEXYL-(2-METHYLPHENYL)PHOSPHINE

Base Information

• Chemical Name: DICYCLOHEXYL-(2-METHYLPHENYL)PHOSPHINE
• CAS No.: 173593-25-4
• Molecular Formula: C19H29P
• Molecular Weight: 288.40700
• Hs Code.: 2931900090
• Mol file: 173593-25-4.mol

Synonyms:(o-Tolyl)dicyclohexylphosphine;Dicyclohexyl(o-tolyl)phosphine;dicyclohexyl(2-methylphenyl)phosphane;Dicyclohexyl(2-methylphenyl)phosphine;

Chemical Property of DICYCLOHEXYL-(2-METHYLPHENYL)PHOSPHINE

Chemical Property:

• Vapor Pressure: 1.57E-06mmHg at 25°C
• Melting Point: 90-93 °C
• Boiling Point: 409.1±24.0 °C(Predicted)
• PSA: 13.59000
• LogP: 5.76760
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%, ^*data from raw suppliers

Dicyclohexyl(o-tolyl)phosphine 95+% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Dicyclohexyl(2-methylphenyl)phosphine [PCy2(o-Tol)] may be used along with [IrCl(cod)]2 to form a complex that can catalyze the addition of aliphatic acid chlorides to terminal alkynes to form (Z)-β-chloro-α,β-unsaturated ketones.

Technology Process of DICYCLOHEXYL-(2-METHYLPHENYL)PHOSPHINE

There total 2 articles about DICYCLOHEXYL-(2-METHYLPHENYL)PHOSPHINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-methylphenyl bromide (95-46-5) + dicyclohexylphosphane (829-84-5) → bis(2-methylphenyl)dicyclohexylphosphane (173593-25-4)

Guidance literature:

With bis(η3-allyl-μ-chloropalladium(II)); potassium hydroxide; In water; at 100 ℃; Inert atmosphere;

DOI:10.1055/s-0036-1590926

Reference yield:

dicyclohexyl(o-tolyl)phosphine borane complex → bis(2-methylphenyl)dicyclohexylphosphane (173593-25-4)

Guidance literature:

With Quinuclidine; In toluene; at 30 ℃; Kinetics;

DOI:10.1021/acs.joc.1c02729

Reference yield: 94.0%

bis(2-methylphenyl)dicyclohexylphosphane (173593-25-4) + dimethylsulfide borane complex (13292-87-0) → dicyclohexyl(o-tolyl)phosphine borane complex

Guidance literature:

In dichloromethane; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1021/acs.joc.1c02729

upstream raw materials:

2-methylphenyl bromide

dicyclohexylphosphane

Downstream raw materials:

(acetylacetonato)carbonylrhodium(I) bis(2-methylphenyl)dicyclohexylphosphane

Refernces

• 1、 Hirai, Yoshinori,Uozumi, Yasuhiro. "Preparation of Aryl(dicyclohexyl)phosphines by C-P Bond-Forming Cross-Coupling in Water Catalyzed by an Amphiphilic-Resin-Supported Palladium Complex". supporting information. p. 2966 - 2970. Retrieved 2017/10/26.