3-Octadecyloxy-1-propanol

Base Information

• Chemical Name: 3-Octadecyloxy-1-propanol
• CAS No.: 17367-36-1
• Molecular Formula: C21H44O2
• Molecular Weight: 328.57300
• Mol file: 17367-36-1.mol

Synonyms:3-octadecyloxypropan-1-ol;3-(octadecyloxy)propanol;1-O-octadecyl-1,3-propanediol;3-octadecyloxy-propan-1-ol;1,3-Propylenglycolmonooctadecylether;3-Octadecyloxy-propanol-(1);

Chemical Property of 3-Octadecyloxy-1-propanol

Chemical Property:

• Vapor Pressure: 1.71E-09mmHg at 25°C
• PSA: 29.46000
• LogP: 6.64690

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Octadecyloxy-1-propanol

There total 5 articles about 3-Octadecyloxy-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C40H58O2 (17367-34-9) → 3-octadecyloxy-1-propanol (17367-36-1)

Guidance literature:

With trifluoroacetic acid; In dichloromethane;

Reference yield:

1-Bromooctadecane (112-89-0) + trimethyleneglycol (504-63-2) → 3-octadecyloxy-1-propanol (17367-36-1)

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; dimethyl sulfoxide; for 2h; Ambient temperature;

DOI:10.1248/cpb.30.3260

Reference yield:

1-octadecyl methanesulfonate (31081-59-1) → 3-octadecyloxy-1-propanol (17367-36-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydride / N,N-dimethyl-formamide

2: trifluoroacetic acid / dichloromethane

With sodium hydride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;

upstream raw materials:

1-octadecanol

trimethyleneglycol

1-Bromooctadecane

C₄₀H₅₈O₂

Downstream raw materials:

1-O-octadecyl-1,3-propanediol-3-phospho-ganciclovir

ethyl 3-(octadecyloxy)propyl [3-({[4-(benzyloxy)-5H-pyrrolo[3,2-d]pyrimidin-7-yl]methyl}amino)propyl]phosphonate

bis[3-(octadecyloxy)propyl] [3-({[4-(benzyloxy)-5H-pyrrolo[3,2-d]pyrimidin-7-yI]methyl}amino)propyl]phosphonate

benzyl N-(3-{bis[3-(octadecyloxy)propoxy]phosphoryl}propyl)carbamate