benzyl N-(3-{bis[3-(octadecyloxy)propoxy]phosphoryl}propyl)carbamate

Base Information

• Chemical Name: benzyl N-(3-{bis[3-(octadecyloxy)propoxy]phosphoryl}propyl)carbamate
• CAS No.: 1404216-66-5
• Molecular Formula: C₅₃H₁₀₀NO₇P
• Molecular Weight: 894.353
• Mol file: 1404216-66-5.mol

Synonyms:benzyl N-(3-{bis[3-(octadecyloxy)propoxy]phosphoryl}propyl)carbamate

Chemical Property of benzyl N-(3-{bis[3-(octadecyloxy)propoxy]phosphoryl}propyl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of benzyl N-(3-{bis[3-(octadecyloxy)propoxy]phosphoryl}propyl)carbamate

There total 1 articles about benzyl N-(3-{bis[3-(octadecyloxy)propoxy]phosphoryl}propyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-octadecyloxy-1-propanol (17367-36-1) + 3-(benzyloxycarbonylamino)propyl phosphonic acid (96523-35-2) → benzyl N-(3-{bis[3-(octadecyloxy)propoxy]phosphoryl}propyl)carbamate (1404216-66-5)

Guidance literature:

3-(benzyloxycarbonylamino)propyl phosphonic acid; With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; for 3h;

3-octadecyloxy-1-propanol; With pyridine; for 2h;

Reference yield:

benzyl N-(3-{bis[3-(octadecyloxy)propoxy]phosphoryl}propyl)carbamate (1404216-66-5) → bis[3-(octadecyloxy)propyl] [3-({[4-(benzyloxy)-5H-pyrrolo[3,2-d]pyrimidin-7-yI]methyl}amino)propyl]phosphonate (1404216-68-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrogen; trifluoroacetic acid / palladium 10% on activated carbon / methanol / 40 °C / 760.05 Torr

2.1: methanol / 18 h / 60 °C

2.2: 0.5 h / 30 °C

With methanol; hydrogen; trifluoroacetic acid; palladium 10% on activated carbon; In methanol;

upstream raw materials:

3-octadecyloxy-1-propanol

3-(benzyloxycarbonylamino)propyl phosphonic acid

Downstream raw materials:

bis[3-(octadecyloxy)propyl] [3-({[4-(benzyloxy)-5H-pyrrolo[3,2-d]pyrimidin-7-yI]methyl}amino)propyl]phosphonate