1,5-Dichloro-2-methyl-4-nitrobenzene

Base Information

• Chemical Name: 1,5-Dichloro-2-methyl-4-nitrobenzene
• CAS No.: 7149-77-1
• Molecular Formula: C7H5Cl2NO2
• Molecular Weight: 206.028
• Hs Code.: 2904909090
• European Community (EC) Number: 668-226-8
• NSC Number: 72331
• DSSTox Substance ID: DTXSID50290999
• Nikkaji Number: J81.339G
• Wikidata: Q82028826
• Mol file: 7149-77-1.mol

Synonyms:1,5-Dichloro-2-methyl-4-nitrobenzene;7149-77-1;2,4-Dichloro-5-nitrotoluene;NSC72331;SCHEMBL864500;DTXSID50290999;MFCD00024187;NSC 72331;NSC-72331;AKOS016007188;1,5-Dichloro-2-methyl-4-nitro-benzene;1,5-Dichloro-2-methyl-4-nitrobenzene #;BS-24408;CS-0193518;FT-0725278;E89343;EN300-3260126

Chemical Property of 1,5-Dichloro-2-methyl-4-nitrobenzene

Chemical Property:

• Vapor Pressure: 0.00256mmHg at 25°C
• Boiling Point: 296.3°C at 760 mmHg
• Flash Point: 133°C
• PSA: 45.82000
• Density: 1.456g/cm³
• LogP: 3.73320
• Storage Temp.: 2-8°C
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 204.9697338
• Heavy Atom Count: 12
• Complexity: 183

Purity/Quality:

98.5% ^*data from raw suppliers

2,4-DICHLORO-5-NITROTOLUENE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1Cl)Cl)[N+](=O)[O-]

Technology Process of 1,5-Dichloro-2-methyl-4-nitrobenzene

There total 3 articles about 1,5-Dichloro-2-methyl-4-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2,4-dichlorotoluene (95-73-8) → 1,5-dichloro-2-methyl-4-nitrobenzene (7149-77-1)

Guidance literature:

With nitric acid; In 1,2-dichloro-ethane; at 30 - 35 ℃; for 2h; Temperature; Reagent/catalyst;

Reference yield:

5-chloro-4-methyl-2-nitroaniline (7149-80-6) → 1,5-dichloro-2-methyl-4-nitrobenzene (7149-77-1)

Guidance literature:

Diazotization_.Behandlung der Diazoniumloesung mit CuCl;

Reference yield:

5-chloro-2-methyl-4-nitroaniline (13852-51-2) → 1,5-dichloro-2-methyl-4-nitrobenzene (7149-77-1)

Guidance literature:

Diazotization_.Behandeln mit Kupfer(I)-chlorid in Salzsaeure;

upstream raw materials:

2,4-dichlorotoluene

5-chloro-4-methyl-2-nitroaniline

5-chloro-2-methyl-4-nitroaniline

Downstream raw materials:

2-[[2-(5-Chloro-4-methyl-2-nitro-phenylamino)-ethyl]-(2-hydroxy-ethyl)-amino]-ethanol

5-bromo-2,4-dichlorotoluene

4-(4-isopropylpiperazin-1-yl)-2-methoxy-5-methylaniline

tert-butyl 4-(5-methoxy-2-methyl-4-nitrophenyl) piperazine-1-carboxylate

Refernces

• 1、 -. "FLAVIN DERIVATIVES". Page/Page column 177. . Retrieved 2010/04/03.
• 2、 Choy, Nakyen,Russell,Alvarez, Julio C.,Fider, Alexa. "Synthesis and redox properties of novel alkynyl flavins". . p. 1515 - 1518. Retrieved 2007/10/03.