AKOS B013913

Base Information

Chemical Name:AKOS B013913
CAS No.:17432-00-7
Molecular Formula:C11H11F3O3
Molecular Weight:248.19800
Hs Code.:2918990090
Mol file:17432-00-7.mol

Synonyms:

Suppliers and Price of AKOS B013913

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Methyl-2-[3-(trifluoromethyl)phenoxy]-propanoic acid
1g
$ 168.00

Matrix Scientific
2-Methyl-2-[3-(trifluoromethyl)phenoxy]-propanoic acid
500mg
$ 144.00

Crysdot
2-Methyl-2-(3-(trifluoromethyl)phenoxy)propanoicacid 95+%
5g
$ 407.00

American Custom Chemicals Corporation
2-METHYL-2-[3-(TRIFLUOROMETHYL)PHENOXY]PROPANOIC ACID 95.00%
5G
$ 1155.00

American Custom Chemicals Corporation
2-METHYL-2-[3-(TRIFLUOROMETHYL)PHENOXY]PROPANOIC ACID 95.00%
0.5G
$ 638.00

AK Scientific
2-Methyl-2-[3-(trifluoromethyl)phenoxy]-propanoicacid
1g
$ 276.00

Total 3 raw suppliers

Chemical Property of AKOS B013913

Chemical Property:

PSA：46.53000
LogP:2.94740

Purity/Quality:

98%min ^*data from raw suppliers

2-Methyl-2-[3-(trifluoromethyl)phenoxy]-propanoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:

Useful:

Technology Process of AKOS B013913

There total 3 articles about AKOS B013913 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: ethyl 2-methyl-2-[3-(trifluoromethyl)phenoxy]propanoate

: 17432-00-7
2-methyl-2-[3-(trifluoromethyl)phenoxy]propanoic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol; water;
DOI:10.1021/acs.jmedchem.6b01584

Reference yield:

: 2052-01-9
2-bromo-2-methylpropionic acid

: 98-17-9
3-Trifluoromethylphenol

: 17432-00-7
2-methyl-2-[3-(trifluoromethyl)phenoxy]propanoic acid

Guidance literature:: 3-Trifluoromethylphenol; With sodium hydroxide; In butanone; at 50 ℃; for 2h;

2-bromo-2-methylpropionic acid; In butanone; at 50 ℃; for 12h;
DOI:10.1021/ja400659s

Reference yield:

: 98-17-9
3-Trifluoromethylphenol

: 17432-00-7
2-methyl-2-[3-(trifluoromethyl)phenoxy]propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h

1.2: 16 h / 20 °C

2.1: sodium hydroxide / tetrahydrofuran; methanol; water

With potassium carbonate; sodium hydroxide; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.6b01584