Pyrrolidine, 2-(azidomethyl)-, (2S)-

Base Information

Chemical Name:Pyrrolidine, 2-(azidomethyl)-, (2S)-
CAS No.:174698-95-4
Molecular Formula:C5H10N4
Molecular Weight:126.161
Hs Code.:

Synonyms:L-proline methylazide;(S)-2-(azidomethyl)pyrrolidine;2-(azidomethyl)pyrrolidine;L-N-2-azidomethylpyrrolidine;(S)-azidomethylpyrrolidine;L-AMP;(S)-2-Azidomethyl-pyrrolidine;

Suppliers and Price of Pyrrolidine, 2-(azidomethyl)-, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Activate Scientific
(S)-2-(Azidomethyl)pyrrolidine HCl 95% ee
5 g
$ 1458.00

Activate Scientific
(S)-2-(Azidomethyl)pyrrolidine HCl 95% ee
1 g
$ 471.00

Acrotein
(S)-2-(Azidomethyl)pyrrolidineHCl 97%
0.5g
$ 256.67

ACHEMBLOCK
(S)-2-(Azidomethyl)pyrrolidinehydrochloride 97%
1G
$ 470.00

Total 3 raw suppliers

Chemical Property of Pyrrolidine, 2-(azidomethyl)-, (2S)-

Chemical Property:

PSA：61.78000
LogP:0.83026

Purity/Quality:

99% ^*data from raw suppliers

(S)-2-(Azidomethyl)pyrrolidine HCl 95% ee ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Pyrrolidine, 2-(azidomethyl)-, (2S)-

There total 5 articles about Pyrrolidine, 2-(azidomethyl)-, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 168049-26-1
tert-butyl (2S)-2-(azidomethyl)-1-pyrrolidinecarboxylate

: 174698-95-4
(2S)-2-azidomethyl-pyrrolidine

Guidance literature:: tert-butyl (2S)-2-(azidomethyl)-1-pyrrolidinecarboxylate; With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃;

With sodium hydrogencarbonate; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1021/jo061657r

Reference yield: 58.0%

: 174698-96-5
C₂HF₃O₂*C₅H₁₀N₄

: 174698-95-4
(2S)-2-azidomethyl-pyrrolidine

Guidance literature:: With sodium hydroxide; In water; Cooling with ice;
DOI:10.1021/jacs.9b11877

Reference yield:

: 86661-32-7
(S)-tert-butyl 2-((tosyloxy)methyl)pyrrolidine-1-carboxylate

: 174698-95-4
(2S)-2-azidomethyl-pyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: NaN₃ / dimethylsulfoxide / 70 °C

2: TFA / CH₂Cl₂ / 0 °C

With sodium azide; trifluoroacetic acid; In dichloromethane; dimethyl sulfoxide;
DOI:10.1016/S0960-894X(01)00664-3