cyclohexyl (4-nitrophenyl) carbonate

Base Information

• Chemical Name: cyclohexyl (4-nitrophenyl) carbonate
• CAS No.: 176787-42-1
• Molecular Formula: C13H15NO5
• Molecular Weight: 265.266
• Mol file: 176787-42-1.mol

Synonyms:cyclohexyl 4-nitrophenyl-carbonate;cyclohexyl 4-nitrophenyl carbonate;Carbonic acid cyclohexyl ester 4-nitro-phenyl ester;

Chemical Property of cyclohexyl (4-nitrophenyl) carbonate

Chemical Property:

• PSA: 81.35000
• LogP: 3.96610

Purity/Quality:

Carbonic acid cyclohexyl ester 4-nitrophenyl ester 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclohexyl (4-nitrophenyl) carbonate

There total 3 articles about cyclohexyl (4-nitrophenyl) carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-Nitrophenyl chloroformate (7693-46-1) + cyclohexanol (108-93-0) → cyclohexyl (4-nitrophenyl) carbonate (176787-42-1)

Guidance literature:

With pyridine; In tetrahydrofuran; at 0 - 20 ℃; for 3.5h;

Reference yield: 84.0%

→ cyclohexyl (4-nitrophenyl) carbonate (176787-42-1)

Guidance literature:

Reference yield:

aqueous potassium hydrogen sulfate + 4-Nitrophenyl chloroformate (7693-46-1) → cyclohexyl (4-nitrophenyl) carbonate (176787-42-1)

Guidance literature:

With triethylamine; In tetrahydrofuran; ethyl acetate; cyclohexanol;

upstream raw materials:

4-Nitrophenyl chloroformate

cyclohexanol

Refernces

• 1、 -. "HEPATITIS C VIRUS NS3/4A PROTEASE INHIBITORS". Paragraph 00133-00134; 00147; 00169. . Retrieved 2020/12/29.
• 2、 -. "ARYLAMIDINE DERIVATIVE, SALT THEREOF AND ANTIFUNGAL CONTAINING THESE". Page/Page column 27. . Retrieved 2008/06/13.