Ethyl 3,3-diphenylacrylate

Base Information

• Chemical Name: Ethyl 3,3-diphenylacrylate
• CAS No.: 17792-17-5
• Molecular Formula: C17H16O2
• Molecular Weight: 252.313
• DSSTox Substance ID: DTXSID30432294
• Nikkaji Number: J331.216J
• Mol file: 17792-17-5.mol

Synonyms:ethyl 3,3-diphenylacrylate;Ethyl 3,3-diphenylprop-2-enoate;17792-17-5;2-Propenoic acid, 3,3-diphenyl-, ethyl ester;SCHEMBL1070286;Ethyl3,3-diphenylprop-2-enoate;DTXSID30432294;SIVYACOIQCOIKW-UHFFFAOYSA-N;3,3-Diphenylacrylic acid ethyl ester;3,3-diphenyl-acrylic acid ethyl ester;EN300-1091720;I(2)-PhenylzimtsA currencyureA currencythylester

Chemical Property of Ethyl 3,3-diphenylacrylate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 252.115029749
• Heavy Atom Count: 19
• Complexity: 287

Purity/Quality:

98% HPLC ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C=C(C1=CC=CC=C1)C2=CC=CC=C2

Technology Process of Ethyl 3,3-diphenylacrylate

There total 75 articles about Ethyl 3,3-diphenylacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

iodobenzene (591-50-4) + ethyl acrylate (140-88-5,9003-32-1) → ethyl 3,3-diphenylacrylate (17792-17-5)

Guidance literature:

With silver(I) acetate; palladium diacetate; acetic acid; at 110 ℃; for 6h; Inert atmosphere;

DOI:10.1039/c6ob01527a

Reference yield: 96.0%

benzophenone (119-61-9) + diethoxyphosphoryl-acetic acid ethyl ester (867-13-0) → ethyl 3,3-diphenylacrylate (17792-17-5)

Guidance literature:

diethoxyphosphoryl-acetic acid ethyl ester; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.5h; Inert atmosphere;

benzophenone; In tetrahydrofuran; mineral oil; Inert atmosphere;

DOI:10.1021/jacs.1c04719

Reference yield: 96.0%

3-ethoxy-1,1-diphenylprop-2-yn-1-ol → ethyl 3,3-diphenylacrylate (17792-17-5)

Guidance literature:

With In³⁺-montmorillonite; In ethanol; 1,2-dichloro-ethane; at 70 ℃; for 0.333333h;

upstream raw materials:

ethyl 3-hydroxy-3,3-diphenylpropanoate

benzophenone

3-Benzenesulfonyl-3,3-diphenyl-propionic acid ethyl ester

N-(diphenylmethylidene)phenylamine

Downstream raw materials:

3,3-diphenylacrylic acid

3,3-diphenylprop-2-en-1-ol

2-bromo-3,3-diphenyl-acrylic acid ethyl ester

ethyl α-benzoyl-ββ-diphenylacrylate

Refernces

• 1、 Sugihara, Takumichi,Takebayashi, Masahiro,Kaneko, Chikara. "Effects of High Pressure on the Heck Reaction. Is It Possible to Control Dehydropalladation of Alkylpalladium Intermediates Having β-Hydrogens?". . p. 5547 - 5550. Retrieved 1995.
• 2、 Morinaga, Akira,Nagao, Kazunori,Ohmiya, Hirohisa,Sawamura, Masaya. "Synthesis of 1,1-Diborylalkenes through a Br?nsted Base Catalyzed Reaction between Terminal Alkynes and Bis(pinacolato)diboron". . p. 15859 - 15862. Retrieved 2015.
• 3、 Zhou, Xibing,Zhang, Guoying,Huang, Renbin,Huang, Hanmin. "Palladium-Catalyzed Allyl-Allyl Reductive Coupling of Allylamines or Allylic Alcohols with H2as Sole Reductant". supporting information. p. 365 - 369. Retrieved 2021/01/26.
• 4、 Tang, Wan-Ying,Chen, Ling,Zheng, Ming,Zhan, Le-Wu,Hou, Jing,Li, Bin-Dong. "Photoinduced Oxidative Alkoxycarbonylation of Alkenes with Alkyl Formates". supporting information. p. 3939 - 3943. Retrieved 2021/05/26.