8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione

Base Information

Chemical Name:8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione
CAS No.:177970-27-3
Molecular Formula:C9H6BrNO3
Molecular Weight:256.056
Hs Code.:2934999090
European Community (EC) Number:809-171-3
DSSTox Substance ID:DTXSID90476255
Wikidata:Q82307314
Mol file:177970-27-3.mol

Synonyms:8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione;177970-27-3;8-bromo-6-methyl-1H-3,1-benzoxazine-2,4-dione;MFCD07439677;8-bromo-6-methyl-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione;F1943-0053;SCHEMBL21751078;DTXSID90476255;AMY31559;CHA97027;AKOS000275352;NS-03890;EN300-238056;A919175

Suppliers and Price of 8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione
1g
$ 201.00

Matrix Scientific
8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 95%+
2.500g
$ 953.00

Matrix Scientific
8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 95%+
1g
$ 436.00

Matrix Scientific
8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 95%+
5g
$ 1442.00

Crysdot
8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 95+%
5g
$ 1360.00

Crysdot
8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 95+%
1g
$ 410.00

Chemenu
8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 95%
1g
$ 387.00

Chemenu
8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 95%
5g
$ 1281.00

American Custom Chemicals Corporation
8-BROMO-6-METHYL-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE 95.00%
5MG
$ 498.34

Alichem
8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione
1g
$ 357.00

Total 8 raw suppliers

Chemical Property of 8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione

Chemical Property:

PSA：63.33000
LogP:1.96450
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:254.95311
Heavy Atom Count:14
Complexity:281

Purity/Quality:

97% ^*data from raw suppliers

8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C(=C1)Br)NC(=O)OC2=O

Technology Process of 8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione

There total 3 articles about 8-Bromo-6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 75-44-5
phosgene

: 13091-43-5
2-amino-3-bromo-5-methylbenzoic acid

: 177970-27-3
8-bromo-6-methyl-2H-benzo[d][1,3]oxazine-2,4(1H)-dione

Guidance literature:: In toluene; at 60 ℃;
DOI:10.1016/S0040-4020(00)00803-6

Reference yield: 97.0%

: 32315-10-9
bis(trichloromethyl) carbonate

: 13091-43-5
2-amino-3-bromo-5-methylbenzoic acid

: 177970-27-3
8-bromo-6-methyl-2H-benzo[d][1,3]oxazine-2,4(1H)-dione

Guidance literature:: In 1,4-dioxane; for 2h; Reflux;

Reference yield:

: 2941-78-8
2-Amino-5-methylbenzoic acid

: 177970-27-3
8-bromo-6-methyl-2H-benzo[d][1,3]oxazine-2,4(1H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / Br₂ / acetic acid / 3 h / 20 °C

2: 100 percent / toluene / 60 °C

With bromine; In acetic acid; toluene; 1: Bromination / 2: Cyclization;
DOI:10.1016/S0040-4020(00)00803-6