2-(3-Nitrobenzoyl)hydrazine-1-carbothioamide

Base Information

Chemical Name:2-(3-Nitrobenzoyl)hydrazine-1-carbothioamide
CAS No.:886-29-3
Molecular Formula:C8H8 N4 O3 S
Molecular Weight:240.243
Hs Code.:
ChEMBL ID:CHEMBL1935521
DSSTox Substance ID:DTXSID90409129
NSC Number:703
Wikidata:Q82214835

Synonyms:886-29-3;NSC703;2-(3-Nitrobenzoyl)hydrazine-1-carbothioamide;CHEMBL1935521;DTXSID90409129;NSC-703;AKOS000295742;1-(M-NITROBENZOYL)-3-THIOSEMICARBAZIDE;2-(3-NITROBENZOYL)HYDRAZINECARBOTHIOAMIDE

Suppliers and Price of 2-(3-Nitrobenzoyl)hydrazine-1-carbothioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 2-(3-Nitrobenzoyl)hydrazine-1-carbothioamide

Chemical Property:

Density:1.509g/cm³
XLogP3:-0.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:240.03171130
Heavy Atom Count:16
Complexity:304

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)[N+](=O)[O-])C(=O)NNC(=S)N

Technology Process of 2-(3-Nitrobenzoyl)hydrazine-1-carbothioamide

There total 4 articles about 2-(3-Nitrobenzoyl)hydrazine-1-carbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 79-19-6
thiosemicarbazide

: 121-90-4
m-nitrobenzoic acid chloride

: 886-29-3
1-(3-nitrobenzoyl)-3-thiosemicarbazide

Guidance literature:: With pyridine; at 0 - 20 ℃; for 12h;
DOI:10.1016/j.bmcl.2011.10.116

Reference yield:

: 121-92-6
3-nitrobenzoic acid

: 886-29-3
1-(3-nitrobenzoyl)-3-thiosemicarbazide

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide; thionyl chloride / dichloromethane / 4 h / Reflux

2: pyridine / 16 h / 20 °C

With pyridine; thionyl chloride; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1016/j.bioorg.2020.104078