2-Bromophenyltrimethylsilane

Base Information

• Chemical Name: 2-Bromophenyltrimethylsilane
• CAS No.: 17878-37-4
• Molecular Formula: C9H13BrSi
• Molecular Weight: 229.192
• DSSTox Substance ID: DTXSID60449294
• Nikkaji Number: J2.447.878E
• Wikidata: Q82268712
• Mol file: 17878-37-4.mol

Synonyms:2-bromophenyltrimethylsilane;17878-37-4;(2-bromophenyl)trimethylsilane;(2-bromophenyl)-trimethylsilane;Benzene, 1-bromo-2-(trimethylsilyl)-;starbld0009486;SCHEMBL3761218;DTXSID60449294;UOSFTLNRCKHHNU-UHFFFAOYSA-N;MFCD32220113;SY271449;EN300-7465917

Chemical Property of 2-Bromophenyltrimethylsilane

Chemical Property:

• Boiling Point: 38 °C(Press: 0.005 Torr)
• PSA: 0.00000
• Density: 1.21±0.1 g/cm3(Predicted)
• LogP: 2.99430
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 227.99699
• Heavy Atom Count: 11
• Complexity: 128

Purity/Quality:

99%,98%, ^*data from raw suppliers

2-Bromophenyltrimethylsilane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)C1=CC=CC=C1Br

Technology Process of 2-Bromophenyltrimethylsilane

There total 9 articles about 2-Bromophenyltrimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,2-bis(trimethylsilyl)benzene (17151-09-6) → 1-bromo-2-(trimethylsilyl)benzene (17878-37-4)

Guidance literature:

With N-Bromosuccinimide; In acetic acid; at 20 ℃; for 2h;

DOI:10.1055/s-0036-1588726

Reference yield: 89.0%

trimethylsilyl trifluoromethanesulfonate (27607-77-8) + 2,3-dibromobenzene (583-53-9) → 1-bromo-2-(trimethylsilyl)benzene (17878-37-4)

Guidance literature:

2,3-dibromobenzene; With n-butyllithium; In tetrahydrofuran; diethyl ether; hexane; at -110 ℃; for 0.5h;

trimethylsilyl trifluoromethanesulfonate; In tetrahydrofuran; diethyl ether; hexane; at -110 - 20 ℃;

DOI:10.1021/ja408712e

Reference yield: 38.0%

chloro-trimethyl-silane (75-77-4) + 2,3-dibromobenzene (583-53-9) → 1-bromo-2-(trimethylsilyl)benzene (17878-37-4)

Guidance literature:

2,3-dibromobenzene; With n-butyllithium; In tetrahydrofuran; diethyl ether; hexane; at -110 ℃; for 1.5h; Inert atmosphere;

chloro-trimethyl-silane; In tetrahydrofuran; diethyl ether; hexane; at -100 - 20 ℃; Inert atmosphere;

DOI:10.1002/anie.201108154

upstream raw materials:

1,2-bis(trimethylsilyl)benzene

chloro-trimethyl-silane

2,3-dibromobenzene

(2-chloro-phenyl)-trimethyl-silane

Downstream raw materials:

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

3-phenylbenzo[d]oxazole-2(3H)-one

1-methyl-3-phenyl-1,3-dihydro-2H-benzo[d]imidazol-2-one

5-methoxy-1-methyl-3-phenyl-1,3-dihydro-2H-benzo[d]imidazol-2-one