[trans-4-(aminomethyl)cyclohexyl]methanol(SALTDATA: FREE)

Base Information

• Chemical Name: [trans-4-(aminomethyl)cyclohexyl]methanol(SALTDATA: FREE)
• CAS No.: 17879-23-1
• Molecular Formula: C8H17NO
• Molecular Weight: 143.229
• Mol file: 17879-23-1.mol

Synonyms:Trans-4-aMniocyclohexanol;trans-4-(aminomethyl)cyclohexanemethanol;1,4-trans-hydroxycyclohexylamine;trans-4-(amino)cyclohexanol;trans-4-hydroxycyclohexylamine;AMINOCYCLOHEXANOL(TRANS-4);[trans-4-(aminomethyl)cyclohexyl]methanol;(1r,4r)-4-aminocyclohexan-1-ol;4-Trans amino cyclohexanol;trans-1-amino-4-cyclohexanol;Trans-4-Amimocyclohexanol;(1r,4r)-4-aminocyclohexanol;trans-4-Aminocyclohe;

Chemical Property of [trans-4-(aminomethyl)cyclohexyl]methanol(SALTDATA: FREE)

Chemical Property:

• PSA: 46.25000
• LogP: 1.44410
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility.: Chloroform(Slightly), DMSO (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

((1r,4r)-4-(Aminomethyl)cyclohexyl)methanol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [trans-4-(aminomethyl)cyclohexyl]methanol(SALTDATA: FREE)

There total 1 articles about [trans-4-(aminomethyl)cyclohexyl]methanol(SALTDATA: FREE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

trans-4-aminomethyl-cyclohexyl-carboxylic acid (1197-18-8) → trans-[4-(aminomethyl)cyclohexyl]methanol (17879-23-1)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 3h; Reflux;

DOI:10.1016/j.bmcl.2010.03.085

Reference yield: 70.0%

trans-[4-(aminomethyl)cyclohexyl]methanol (17879-23-1) + benzyl chloroformate (501-53-1,94274-21-2) → [trans-4-(N-benzyloxycarbonylaminomethyl)cyclohexyl]methanol (1233224-64-0)

Guidance literature:

With sodium carbonate; In water; at 0 - 20 ℃;

DOI:10.1016/j.bmcl.2010.03.085

Reference yield:

trans-[4-(aminomethyl)cyclohexyl]methanol (17879-23-1) + methyl chloroformate (79-22-1) → ((1r,4r)-4-((methylamino)methyl)cyclohexyl)methanol (554453-93-9)

Guidance literature:

trans-[4-(aminomethyl)cyclohexyl]methanol; methyl chloroformate; With triethylamine; In dichloromethane; at 0 ℃; for 0.75h;

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0.45 ℃;

upstream raw materials:

trans-4-aminomethyl-cyclohexyl-carboxylic acid

Downstream raw materials:

trans-4-(acetylaminomethyl)cyclohexylmethyl benzoate

[trans-4-(N-benzyloxycarbonylaminomethyl)cyclohexyl]methanol

9-[trans-4-(N-benzyloxycarbonylaminomethyl)cyclohexylmethyl]adenine

9-(trans-4-aminomethylcyclohexylmethyl)adenine