N-[3-(4-chlorophenoxy)-4-pyridinyl]methanesulfonamide

Base Information

Chemical Name:N-[3-(4-chlorophenoxy)-4-pyridinyl]methanesulfonamide
CAS No.:180194-80-3
Molecular Formula:C12H11ClN2O3S
Molecular Weight:298.75
Hs Code.:
DSSTox Substance ID:DTXSID50441202
Nikkaji Number:J754.290I
ChEMBL ID:CHEMBL388625

Synonyms:N-[3-(4-chlorophenoxy)-4-pyridinyl]methanesulfonamide;180194-80-3;CHEMBL388625;N-[3-(4-chlorophenoxy)pyridin-4-yl]methanesulfonamide;DTXSID50441202;BDBM50158456;N-[3-(4-Chlorophenoxy)-4-pyridyl]methanesulfonamide

Suppliers and Price of N-[3-(4-chlorophenoxy)-4-pyridinyl]methanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[3-(4-chlorophenoxy)-4-pyridinyl]methanesulfonamide

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:298.0178911
Heavy Atom Count:19
Complexity:377

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)NC1=C(C=NC=C1)OC2=CC=C(C=C2)Cl

Technology Process of N-[3-(4-chlorophenoxy)-4-pyridinyl]methanesulfonamide

There total 6 articles about N-[3-(4-chlorophenoxy)-4-pyridinyl]methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 124-63-0
methanesulfonyl chloride

: 180194-77-8
4-amino-3-(4-chlorophenoxy)pyridine

: 180194-80-3
N-[3-(4-Chloro-phenoxy)-pyridin-4-yl]-methanesulfonamide

Guidance literature:: With sodium hydroxide; In diethyl ether; at 0 - 3 ℃;
DOI:10.1016/0223-5234(96)89162-8

Reference yield:

: 1678-49-5
3-Bromo-4-nitropyridine N-oxide

: 180194-80-3
N-[3-(4-Chloro-phenoxy)-pyridin-4-yl]-methanesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: aq. NaOH

1.2: 47 percent / acetonitrile / Heating

2.1: Fe; aq. acetic acid / Heating

3.1: K₂CO₃ / acetonitrile

With sodium hydroxide; iron; potassium carbonate; acetic acid; In acetonitrile;
DOI:10.1021/jm049480l

Reference yield:

: 180194-75-6
4-nitro-3-(4-chlorophenoxy)pyridine N-oxide

: 180194-80-3
N-[3-(4-Chloro-phenoxy)-pyridin-4-yl]-methanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: Fe; aq. acetic acid / Heating

2: K₂CO₃ / acetonitrile

With iron; potassium carbonate; acetic acid; In acetonitrile;
DOI:10.1021/jm049480l