2,5-Bis(chloromethyl)-3,4-diphenylthiophene

Base Information

Chemical Name:2,5-Bis(chloromethyl)-3,4-diphenylthiophene
CAS No.:181218-41-7
Molecular Formula:C18H14Cl2S
Molecular Weight:333.281
Hs Code.:
DSSTox Substance ID:DTXSID30598682
Nikkaji Number:J1.132.980B
Wikidata:Q82494466
Mol file:181218-41-7.mol

Synonyms:2,5-Bis(chloromethyl)-3,4-diphenylthiophene;181218-41-7;SCHEMBL3611610;DTXSID30598682

Suppliers and Price of 2,5-Bis(chloromethyl)-3,4-diphenylthiophene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,5-Bis(chloromethyl)-3,4-diphenylthiophene

Chemical Property:

XLogP3:5.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:332.0193270
Heavy Atom Count:21
Complexity:280

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(SC(=C2C3=CC=CC=C3)CCl)CCl

Technology Process of 2,5-Bis(chloromethyl)-3,4-diphenylthiophene

There total 7 articles about 2,5-Bis(chloromethyl)-3,4-diphenylthiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 16939-13-2
3,4-diphenylthiophene

: 181218-41-7
3,4-diphenyl-2,5-bis(chloromethyl)thiophene

Guidance literature:: With hydrogenchloride; acetic anhydride; at 70 ℃; for 4.5h;
DOI:10.1021/ma047940e

Reference yield:

: 87694-43-7
3,4-Diphenyl-2,5-thiophendimethanol

: 181218-41-7
3,4-diphenyl-2,5-bis(chloromethyl)thiophene

Guidance literature:: With thionyl chloride; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1021/ma047940e

Reference yield:

: 98-80-6
phenylboronic acid

: 181218-41-7
3,4-diphenyl-2,5-bis(chloromethyl)thiophene

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / KF / Pd(PPh₃)4 / H₂O; toluene / 18 h / Heating

2: 98 percent / HCl; Ac₂O / 4.5 h / 70 °C

With hydrogenchloride; potassium fluoride; acetic anhydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; toluene;
DOI:10.1021/ma047940e